日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM

TIGIT 和 PD-1 双检查点阻断可增强 GBM 的抗肿瘤免疫力和生存率

Alice L Hung, Russell Maxwell, Debebe Theodros, Zineb Belcaid, Dimitrios Mathios, Andrew S Luksik, Eileen Kim, Adela Wu, Yuanxuan Xia, Tomas Garzon-Muvdi, Christopher Jackson, Xiaobu Ye, Betty Tyler, Mark Selby, Alan Korman, Bryan Barnhart, Su-Myeong Park, Je-In Youn, Tamrin Chowdhury, Chul-Kee Park

Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden

表观遗传治疗激活小鼠卵巢癌中的 I 型干扰素信号传导以减少免疫抑制和肿瘤负担

Meredith L Stone, Katherine B Chiappinelli, Huili Li, Lauren M Murphy, Meghan E Travers, Michael J Topper, Dimitrios Mathios, Michael Lim, Ie-Ming Shih, Tian-Li Wang, Chien-Fu Hung, Vipul Bhargava, Karla R Wiehagen, Glenn S Cowley, Kurtis E Bachman, Reiner Strick, Pamela L Strissel, Stephen B Baylin

Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma

激动剂抗GITR单克隆抗体和立体定向放射治疗可诱导小鼠颅内胶质瘤细胞产生免疫介导的生存优势

Mira A Patel # ,Jennifer E Kim # ,Debebe Theodros ,Ada Tam ,Esteban Velarde ,Christina M Kochel ,Brian Francica ,Thomas R Nirschl ,Ali Ghasemzadeh ,Dimitrios Mathios ,Sarah Harris-Bookman ,Christopher C Jackson ,Christina Jackson ,Xiaobu Ye ,Phuoc T Tran ,Betty Tyler ,Vladimir Coric ,Mark Selby ,Henry Brem ,Charles G Drake ,Drew M Pardoll ,Michael Lim

Therapeutic administration of IL-15 superagonist complex ALT-803 leads to long-term survival and durable antitumor immune response in a murine glioblastoma model

IL-15 超激动剂复合物 ALT-803 的治疗性给药可使小鼠胶质母细胞瘤模型获得长期生存和持久的抗肿瘤免疫反应

Dimitrios Mathios, Chul-Kee Park, Warren D Marcus, Sarah Alter, Peter R Rhode, Emily K Jeng, Hing C Wong, Drew M Pardoll, Michael Lim