Synthesis and quantitative structure-activity relationship of imidazotetrazine prodrugs with activity independent of O6-methylguanine-DNA-methyltransferase, DNA mismatch repair, and p53

咪唑并四嗪前药的合成及定量构效关系，其活性不依赖于 O6-甲基鸟嘌呤-DNA 甲基转移酶、DNA 错配修复和 p53