日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Long-read RNA sequencing of archival tissues reveals novel genes and transcripts associated with clear cell renal cell carcinoma recurrence and immune evasion

对档案组织进行长读 RNA 测序揭示了与透明细胞肾细胞癌复发和免疫逃避相关的新基因和转录本

Joshua Lee, Elizabeth A Snell, Joanne Brown, Charlotte E Booth, Rosamonde E Banks, Daniel J Turner, Naveen S Vasudev, Dimitris Lagos

Inhibition of the Na+/K+-ATPase by cardiac glycosides suppresses expression of the IDO1 immune checkpoint in cancer cells by reducing STAT1 activation

强心苷抑制 Na+/K+-ATPase 可降低 STAT1 活性,从而抑制癌细胞中 IDO1 免疫检查点的表达

Mia A Shandell, Alina L Capatina, Samantha M Lawrence, William J Brackenbury, Dimitris Lagos

Mathematical modelling of activation-induced heterogeneity in TNF, IL6, NOS2, and IL1β expression reveals cell state transitions underpinning macrophage responses to LPS

TNF、IL6、NOS2 和 IL1β 表达中活化诱导异质性的数学建模揭示了巨噬细胞对 LPS 反应的细胞状态转变

Shoumit Dey, Dave Boucher, Jon Pitchford, Dimitris Lagos

Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells

Malat1 通过促进 Th 细胞中 Maf 和 IL-10 的表达来抑制对感染的免疫

James P Hewitson, Katie A West, Kylie R James, Gulab Fatima Rani, Nidhi Dey, Audrey Romano, Najmeeyah Brown, Sarah A Teichmann, Paul M Kaye, Dimitris Lagos

Characterisation of baseline microbiological and host factors in an inception cohort of people with surgical wounds healing by secondary intention reveals circulating IL-6 levels as a potential predictive biomarker of healing

对一组通过二期愈合手术伤口的初始患者进行基线微生物和宿主因素的表征,揭示了循环 IL-6 水平是愈合的潜在预测生物标志物

Hannah Buckley, Jo Dumville, Michael Hodgkinson, Debbie Wearmouth, Gavin Barlow, Marjan van der Woude, Nicky Cullum, Ian Chetter, Dimitris Lagos

miR-132 suppresses transcription of ribosomal proteins to promote protective Th1 immunity

miR-132 抑制核糖体蛋白转录以促进保护性 Th1 免疫

James P Hewitson, Kunal M Shah, Najmeeyah Brown, Paul Grevitt, Sofia Hain, Katherine Newling, Tyson V Sharp, Paul M Kaye, Dimitris Lagos

Tissue and host species-specific transcriptional changes in models of experimental visceral leishmaniasis

实验性内脏利什曼病模型中的组织和宿主物种特异性转录变化

Helen Ashwin, Karin Seifert, Sarah Forrester, Najmeeyah Brown, Sandy MacDonald, Sally James, Dimitris Lagos, Jon Timmis, Jeremy C Mottram, Simon L Croft, Paul M Kaye

MicroRNA-155 induction via TNF-α and IFN-γ suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells

通过 TNF-α 和 IFN-γ 诱导的 microRNA-155 可抑制人类原代细胞中程序性死亡配体 1 (PD-L1) 的表达

Daniel Yee, Kunal M Shah, Mark C Coles, Tyson V Sharp, Dimitris Lagos

S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells

S6K2 介导的 TRBP 调节是人类原代淋巴管内皮细胞中 miRNA 表达的决定因素

Matthew J Warner, Katherine S Bridge, James P Hewitson, Michael R Hodgkinson, Alex Heyam, Bailey C Massa, Jessica C Haslam, Maria Chatzifrangkeskou, Gareth J O Evans, Michael J Plevin, Tyson V Sharp, Dimitris Lagos

Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells

卡波西肉瘤疱疹病毒微小RNA诱导受感染细胞的代谢转化

Ohad Yogev, Dimitris Lagos, Tariq Enver, Chris Boshoff