日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting Hypoxia Sensitizes TNBC to Cisplatin and Promotes Inhibition of Both Bulk and Cancer Stem Cells

靶向缺氧可增强三阴性乳腺癌对顺铂的敏感性,并促进对肿瘤干细胞和癌干细胞的抑制。

Sulaiman, Andrew; McGarry, Sarah; Chambers, Jason; Al-Kadi, Emil; Phan, Alexandra; Li, Li; Mediratta, Karan; Dimitroulakos, Jim; Addison, Christina; Li, Xuguang; Wang, Lisheng

Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells

mTORC1、HDAC 和 ESR1α 的共同抑制可延缓三阴性乳腺癌的生长并抑制癌症干细胞

Andrew Sulaiman, Sarah McGarry, Ka Mien Lam, Sara El-Sahli, Jason Chambers, Shelby Kaczmarek, Li Li, Christina Addison, Jim Dimitroulakos, Angel Arnaout, Carolyn Nessim, Zemin Yao, Guang Ji, Haiyan Song, Sheng Liu, Ying Xie, Suresh Gadde, Xuguang Li, Lisheng Wang

Dual inhibition of Wnt and Yes-associated protein signaling retards the growth of triple-negative breast cancer in both mesenchymal and epithelial states

Wnt 和 Yes 相关蛋白信号的双重抑制可延缓间质和上皮状态下三阴性乳腺癌的生长

Andrew Sulaiman, Sarah McGarry, Li Li, Deyong Jia, Sarah Ooi, Christina Addison, Jim Dimitroulakos, Angel Arnaout, Carolyn Nessim, Zemin Yao, Guang Ji, Haiyan Song, Suresh Gadde, Xuguang Li, Lisheng Wang

Activating Transcription Factor 3 as a Novel Regulator of Chemotherapy Response in Breast Cancer

激活转录因子 3 作为乳腺癌化疗反应的新型调节剂

Mohamed S Hasim, Carolyn Nessim, Patrick J Villeneuve, Barbara C Vanderhyden, Jim Dimitroulakos

Induction of Activating Transcription Factor 3 Is Associated with Cisplatin Responsiveness in Non-Small Cell Lung Carcinoma Cells

激活转录因子3的诱导与非小细胞肺癌细胞对顺铂的反应性相关

Bar, Jair; Hasim, Mohamed S; Baghai, Tabassom; Niknejad, Nima; Perkins, Theodore J; Stewart, David J; Sekhon, Harmanjatinder S; Villeneuve, Patrick J; Dimitroulakos, Jim

A phase I study of high-dose rosuvastatin with standard dose erlotinib in patients with advanced solid malignancies

一项针对晚期实体恶性肿瘤患者的高剂量瑞舒伐他汀联合标准剂量厄洛替尼的I期研究

Goss, Glenwood D; Jonker, Derek J; Laurie, Scott A; Weberpals, Johanne I; Oza, Amit M; Spaans, Johanna N; la Porte, Charles; Dimitroulakos, Jim

Focal Adhesion Kinase Inhibitors in Combination with Erlotinib Demonstrate Enhanced Anti-Tumor Activity in Non-Small Cell Lung Cancer

粘着斑激酶抑制剂与厄洛替尼联合使用可增强非小细胞肺癌的抗肿瘤活性

Grant A Howe, Bin Xiao, Huijun Zhao, Khalid N Al-Zahrani, Mohamed S Hasim, James Villeneuve, Harmanjatinder S Sekhon, Glenwood D Goss, Luc A Sabourin, Jim Dimitroulakos, Christina L Addison

miR-105 inhibits prostate tumour growth by suppressing CDK6 levels

miR-105通过抑制CDK6水平来抑制前列腺肿瘤生长

Honeywell, D Rice; Cabrita, Miguel A; Zhao, Huijun; Dimitroulakos, Jim; Addison, Christina L

The effect of the histone deacetylase inhibitor M344 on BRCA1 expression in breast and ovarian cancer cells

组蛋白去乙酰化酶抑制剂M344对乳腺癌和卵巢癌细胞中BRCA1表达的影响

Weberpals, Johanne I; O'Brien, Anna M; Niknejad, Nima; Garbuio, Kyla D; Clark-Knowles, Katherine V; Dimitroulakos, Jim

Activating Transcription Factor 3 regulates in part the enhanced tumour cell cytotoxicity of the histone deacetylase inhibitor M344 and cisplatin in combination

激活转录因子3部分调节组蛋白去乙酰化酶抑制剂M344与顺铂联合用药增强的肿瘤细胞毒性。

St Germain, Carly; O'Brien, Anna; Dimitroulakos, Jim