日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Clinically advanced NLRP3 inhibitor modulates microglial transcriptome and alleviates α-synuclein-induced progression of parkinsonism

临床上先进的NLRP3抑制剂可调节小胶质细胞转录组,并减轻α-突触核蛋白诱导的帕金森病进展。

Luque, Maria; Matic, Magdalena; Heras-Garvin, Antonio; Amo-Aparicio, Jesus; Luk, Kelvin C; Haindl, Michaela Tanja; Khalil, Michael; Skouras, Damaris B; Dinarello, Charles A; Stefanova, Nadia

Human Alpha-1 Antitrypsin Suppresses Melanoma Growth by Promoting Tumor Differentiation and CD8(+) T-Cell-Mediated Immunity

人α1-抗胰蛋白酶通过促进肿瘤分化和CD8(+) T细胞介导的免疫来抑制黑色素瘤生长

Yamauchi, Takeshi; Luo, Yuchun; Menon, Dinoop Ravindran; Couts, Kasey; Khan, Sana; Goel, Aanchal; Dinarello, Charles A; Zhai, Zili; Fujita, Mayumi

Interleukin-1 signaling and CD4(+) T cells control B cell recruitment to the lungs in chronic beryllium disease

白细胞介素-1信号通路和CD4(+) T细胞控制慢性铍病中B细胞向肺部的募集

Gaballa, Joseph M; Valdez, Caley; Mack, Douglas G; Minhajuddin, Faiz; Raza, Masoom; Mohammad, Tabrez A; Martin, Allison K; Getahun, Andrew; Dinarello, Charles A; Fontenot, Andrew P; Atif, Shaikh M

Micro- and nano-plastics induce inflammation and cell death in human cells

微塑料和纳米塑料会诱发人体细胞炎症和细胞死亡。

Bishop, Brandon; Webber, William S; Atif, Shaikh M; Ley, Ashley; Pankratz, Karl A; Kostelecky, Rachael; Colgan, Sean P; Dinarello, Charles A; Zhang, Wei; Li, Suzhao

Interleukin-38 is a negative regulator of trained immunity-A retrospective multi-omics study

白细胞介素-38是训练免疫的负调控因子——一项回顾性多组学研究

Teufel, Lisa U; Matzaraki, Vasiliki; Folkman, Lukas; de Graaf, Dennis M; Horst, Rob Ter; Moorlag, Simone J C F M; Dos Santos, Jéssica C; Mulders-Manders, Catharina M; Krausgruber, Thomas; Dinarello, Charles; Netea, Mihai G; Joosten, Leo A B; Arts, Rob J W

Metabolic reprogramming of the inflammatory response in the nervous system: the crossover between inflammation and metabolism

神经系统炎症反应的代谢重编程:炎症与代谢的交叉

Amo-Aparicio, Jesus; Dinarello, Charles A; Lopez-Vales, Ruben

Screening NLRP3 drug candidates in clinical development: lessons from existing and emerging technologies

NLRP3候选药物临床开发筛选:来自现有技术和新兴技术的经验教训

Tengesdal, Isak W; Banks, Migachelle; Dinarello, Charles A; Marchetti, Carlo

Interleukin-18 Binding Protein (IL-18BP): A Long Journey From Discovery to Clinical Application

白细胞介素-18结合蛋白(IL-18BP):从发现到临床应用的漫长历程

Kim, Soohyun; Yu, Hyeon; Azam, Tania; Dinarello, Charles A

Inflammation promotes aging-associated oncogenesis in the lung

炎症促进肺部衰老相关肿瘤的发生

Pham-Danis, Catherine; Chia, Shi B; Scarborough, Hannah A; Danis, Etienne; Nemkov, Travis; Kleczko, Emily K; Navarro, Andre; Goodspeed, Andrew; Bonney, Elizabeth A; Dinarello, Charles A; Marchetti, Carlo; Nemenoff, Raphael A; Hansen, Kirk; DeGregori, James

NLRP3 and cancer: Pathogenesis and therapeutic opportunities

NLRP3与癌症:发病机制和治疗机遇

Tengesdal, Isak W; Dinarello, Charles A; Marchetti, Carlo