日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The USH3A causative gene clarin1 functions in Müller glia to maintain retinal photoreceptors.

USH3A致病基因clarin1在Müller胶质细胞中发挥作用,以维持视网膜感光细胞

Nonarath Hannah J T, Simpson Samantha L, Slobodianuk Tricia L, Tran Hai, Collery Ross F, Dinculescu Astra, Link Brian A

Retinal Gene Therapy for Usher Syndrome: Current Developments, Challenges, and Perspectives

Usher综合征视网膜基因治疗:当前进展、挑战和展望

Dinculescu, Astra; Link, Brian A; Saperstein, David A

Cone Phosphodiesterase-6γ' Subunit Augments Cone PDE6 Holoenzyme Assembly and Stability in a Mouse Model Lacking Both Rod and Cone PDE6 Catalytic Subunits

在缺乏视杆细胞和视锥细胞PDE6催化亚基的小鼠模型中,视锥细胞磷酸二酯酶-6γ'亚基增强了视锥细胞PDE6全酶的组装和稳定性

Deng, Wen-Tao; Kolandaivelu, Saravanan; Dinculescu, Astra; Li, Jie; Zhu, Ping; Chiodo, Vince A; Ramamurthy, Visvanathan; Hauswirth, William W

Modeling and Preventing Progressive Hearing Loss in Usher Syndrome III

Usher综合征III型进行性听力损失的建模与预防

Geng, Ruishuang; Omar, Akil; Gopal, Suhasini R; Chen, Daniel H-C; Stepanyan, Ruben; Basch, Martin L; Dinculescu, Astra; Furness, David N; Saperstein, David; Hauswirth, William; Lustig, Lawrence R; Alagramam, Kumar N

Gene Therapy in a Large Animal Model of PDE6A-Retinitis Pigmentosa.

在PDE6A-视网膜色素变性大型动物模型中进行基因治疗

Mowat Freya M, Occelli Laurence M, Bartoe Joshua T, Gervais Kristen J, Bruewer Ashlee R, Querubin Janice, Dinculescu Astra, Boye Sanford L, Hauswirth William W, Petersen-Jones Simon M

AAV-Mediated Clarin-1 Expression in the Mouse Retina: Implications for USH3A Gene Therapy

AAV介导的小鼠视网膜中Clarin-1的表达:对USH3A基因治疗的启示

Dinculescu, Astra; Stupay, Rachel M; Deng, Wen-Tao; Dyka, Frank M; Min, Seok-Hong; Boye, Sanford L; Chiodo, Vince A; Abrahan, Carolina E; Zhu, Ping; Li, Qiuhong; Strettoi, Enrica; Novelli, Elena; Nagel-Wolfrum, Kerstin; Wolfrum, Uwe; Smith, W Clay; Hauswirth, William W

Tyrosine-mutant AAV8 delivery of human MERTK provides long-term retinal preservation in RCS rats

利用酪氨酸突变型AAV8递送人MERTK可使RCS大鼠的视网膜长期保持健康

Deng, Wen-Tao; Dinculescu, Astra; Li, Qiuhong; Boye, Sanford L; Li, Jie; Gorbatyuk, Marina S; Pang, Jijing; Chiodo, Vince A; Matthes, Michael T; Yasumura, Douglas; Liu, Li; Alkuraya, Fowzan S; Zhang, Kang; Vollrath, Douglas; LaVail, Matthew M; Hauswirth, William W

Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina

酪氨酸突变型AAV2载体在小鼠视网膜中的新特性

Petrs-Silva, Hilda; Dinculescu, Astra; Li, Qiuhong; Deng, Wen-Tao; Pang, Ji-Jing; Min, Seok-Hong; Chiodo, Vince; Neeley, Andy W; Govindasamy, Lakshmanan; Bennett, Antonette; Agbandje-McKenna, Mavis; Zhong, Li; Li, Baozheng; Jayandharan, Giridhara R; Srivastava, Arun; Lewin, Alfred S; Hauswirth, William W

Alternative splice variants of the USH3A gene Clarin 1 (CLRN1)

USH3A 基因的替代剪接变体 Clarin 1 (CLRN1)

Västinsalo, Hanna; Jalkanen, Reetta; Dinculescu, Astra; Isosomppi, Juha; Geller, Scott; Flannery, John G; Hauswirth, William W; Sankila, Eeva-Marja

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

利用酪氨酸突变型AAV血清型载体高效转导小鼠视网膜

Petrs-Silva, Hilda; Dinculescu, Astra; Li, Qiuhong; Min, Seok-Hong; Chiodo, Vince; Pang, Ji-Jing; Zhong, Li; Zolotukhin, Sergei; Srivastava, Arun; Lewin, Alfred S; Hauswirth, William W