日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Cell-type specific activation of the cGAS-STING pathway in tumor immunotherapy: mechanisms and therapeutic implications

肿瘤免疫治疗中cGAS-STING通路细胞类型特异性激活：机制及治疗意义

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-025-07645-2
Wang, Lusheng; Zhu, Sudi; Ding, Zhixian; Hong, Jie; Zheng, Lijie; Sun, Jiting; Tang, Yu; Chen, Xiaohui; Yong, Xiang; Hu, Mengxue; Jiang, Zhimin; Liu, Yan; Wang, Dan; Tang, Heng
肿瘤
肿瘤免疫
信号转导
STING
cGAS-STING
细胞生物学
免疫/内分泌
发表日期：2026
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TET1 suppresses hepatocellular carcinoma progression by modulating the PI3K/Akt signaling pathways.

TET1 通过调节 PI3K/Akt 信号通路抑制肝细胞癌的进展。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-36334-3
Qi Shuaiyong, Chen Ming, Ding Zhixian, Dai Mike, Wang Lusheng, Chen Jie, Tang Yu, Hu Mengxue, Li Yafei, Tan Kemeng, Li Lili, Jiang Hui, Tang Heng
细胞生物学
AKT
PI3K/Akt
发表日期：2026
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Unveiling the hidden regulators: how post-translational modifications influence the progression and treatment of hepatocellular carcinoma

揭示隐藏的调控因子：翻译后修饰如何影响肝细胞癌的进展和治疗

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2026.1726574
Qi, Shuaiyong; Yong, Xiang; Ding, Zhixian; Hu, Mengxue; Li, Yafen; Li, Lili; Hu, Huaiyuan; Tang, Heng
信号转导
细胞生物学
肿瘤
肿瘤免疫
发表日期：2026
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Activation of the cGAS-STING pathway by clofoctol through mitochondrial damage in triple-negative breast cancer.

氯福醇通过线粒体损伤激活三阴性乳腺癌中的 cGAS-STING 通路。

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-025-07592-y
Wang Lusheng, Zheng Lijie, Yong Xiang, Ding Zhixian, Sun Jiting, Tang Yu, Tang Kemeng, Li Yafen, Chen Jie, Qi Shuaiyong, Hu Huaiyuan, Tang Heng
乳腺癌
信号转导
CGA
CGAS
STING
cGAS-STING
线粒体
发表日期：2025
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Construction and applications of exosome-microneedle integrated systems

外泌体-微针集成系统的构建及应用

期刊:International Journal of Pharmaceutics: X
影响因子:6.4
doi:10.1016/j.ijpx.2025.100360
Zheng, Lijie; Sun, Jiting; Wang, Lusheng; Ding, Zhixian; Tang, Yu; Dai, Mike; Tang, Heng
外泌体
发表日期：2025
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NOX4 serves as a pan-cancer prognostic biomarker and therapeutic target in tumorigenesis.

NOX4 在肿瘤发生过程中可作为泛癌预后生物标志物和治疗靶点

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-09690-9
Sun Jiting, Gong Zhiyuan, Zheng Lijie, Ding Zhixian, Wang Lusheng, Tang Yu, Deng Shizhan, Dong Yonggan, Tang Heng
肿瘤
肿瘤免疫
发表日期：2025
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Hepatocellular carcinoma: pathogenesis, molecular mechanisms, and treatment advances

肝细胞癌：发病机制、分子机制和治疗进展

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2025.1526206
Ding, Zhixian; Wang, Lusheng; Sun, Jiting; Zheng, Lijie; Tang, Yu; Tang, Heng
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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MiR-424-5p acts as an oncogene in Hep3B cells by activating the PI3K/AKT signaling pathway.

miR-424-5p 通过激活 PI3K/AKT 信号通路在 Hep3B 细胞中发挥癌基因的作用。

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2025.1726596
Ding Zhixian, Qi Shuaiyong, Hu Mengxue, Wang Lusheng, Tang Yu, Sun Jiting, Zheng Lijie, Li Yafen, Li Lili, Ma Quangen, Tang Heng
肿瘤
T细胞
肿瘤免疫
信号转导
细胞生物学
AKT
发表日期：2025
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LncRNA SNHG6 promotes proliferation, invasion and migration in colorectal cancer cells by activating TGF-β/Smad signaling pathway via targeting UPF1 and inducing EMT via regulation of ZEB1

LncRNA SNHG6通过靶向UPF1激活TGF-β/Smad信号通路并通过调控ZEB1诱导EMT促进结直肠癌细胞增殖、侵袭和迁移

期刊:International Journal of Medical Sciences
影响因子:3.2
doi:10.7150/ijms.27359
Xinke Wang, Qiuhua Lai, Juan He, Qingyuan Li, Jian Ding, Zhixian Lan, Chuncai Gu, Qun Yan, Yuxin Fang, Xinmei Zhao, Side Liu
信号转导
肿瘤
肠癌
肿瘤细胞
TGF-β
发表日期：2019
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