日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Nighttime safety of daridorexant: Evaluation of responsiveness to an external noise stimulus, postural stability, walking, and cognitive function

达里多雷生夜间安全性：对外部噪声刺激的反应性、姿势稳定性、行走能力和认知功能的评估

期刊:Journal of Psychopharmacology
影响因子:5.5
doi:10.1177/02698811241293997
Magliocca, Massimo; Koopmans, Ingrid; Vaillant, Cedric; Lemoine, Vincent; Zuiker, Rob; Dingemanse, Jasper; Muehlan, Clemens
神经科学
发表日期：2025
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The effect of itraconazole, a strong CYP3A4 inhibitor, on the pharmacokinetics of the first-in-class ACKR3/CXCR7 antagonist, ACT-1004-1239

伊曲康唑（一种强效 CYP3A4 抑制剂）对首创 ACKR3/CXCR7 拮抗剂 ACT-1004-1239 的药代动力学的影响

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.13883
Huynh, Christine; Dingemanse, Jasper; Meyer Zu Schwabedissen, Henriette E; Fonseca, Marlene; Sidharta, Patricia N
CT-1
CYP3A4
发表日期：2024
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Effect of Daridorexant on the Pharmacokinetics of Midazolam, and on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Male Subjects

Daridorexant对健康男性受试者咪达唑仑药代动力学以及华法林药代动力学和药效学的影响

期刊:Drugs in Research & Development
影响因子:2.1
doi:10.1007/s40268-024-00456-8
Zenklusen, Isabelle; Dingemanse, Jasper; Reh, Christian; Gehin, Martine; Kaufmann, Priska
发表日期：2024
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Population pharmacokinetic modeling of daridorexant, a novel dual orexin receptor antagonist

达里多雷生（一种新型双重食欲素受体拮抗剂）的群体药代动力学模型

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.12877
Krause, Andreas; Lott, Dominik; Brussee, Janneke M; Muehlan, Clemens; Dingemanse, Jasper
信号转导
发表日期：2023
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Evaluation of the cytochrome P450 2C19 and 3A4 inhibition potential of the complement factor 5a receptor 1 antagonist ACT-1014-6470 in vitro and in vivo

体外和体内评价补体因子5a受体1拮抗剂ACT-1014-6470对细胞色素P450 2C19和3A4的抑制潜力

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.13525
Anliker-Ort, Marion; Dingemanse, Jasper; Delahaye, Stephane; Janů, Luboš; van den Anker, John; Berger, Benjamin; Kaufmann, Priska
信号转导
细胞生物学
CT-1
免疫/内分泌
发表日期：2023
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Modeling time-delayed concentration-QT effects with ACT-1014-6470, a novel oral complement factor 5a receptor 1 (C5a(1) receptor) antagonist

利用新型口服补体因子5a受体1（C5a(1)受体）拮抗剂ACT-1014-6470模拟时间延迟浓度-QT效应

期刊:Pharmacology Research & Perspectives
影响因子:2.3
doi:10.1002/prp2.1112
Anliker-Ort, Marion; Hsin, Chih-Hsuan; Krause, Andreas; Pfister, Marc; van den Anker, John; Dingemanse, Jasper; Kaufmann, Priska
信号转导
CT-1
免疫/内分泌
发表日期：2023
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Effect of nivasorexant (ACT-539313), a selective orexin-1-receptor antagonist, on multiple cytochrome P450 probe substrates in vitro and in vivo using a cocktail approach in healthy subjects

尼瓦索雷生（ACT-539313，一种选择性食欲素-1受体拮抗剂）对多种细胞色素P450探针底物在体外和体内（采用混合药物法）健康受试者中的影响

期刊:Pharmacology Research & Perspectives
影响因子:2.3
doi:10.1002/prp2.1143
Berger, Benjamin; Kaufmann, Priska; Berse, Matthias; Treiber, Alexander; Grignaschi, Nathalie; Dingemanse, Jasper
信号转导
细胞生物学
发表日期：2023
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Driving Performance after Bedtime Administration of Daridorexant, Assessed in a Sensitive Simulator

睡前服用达里多雷生后驾驶性能的敏感模拟器评估

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.2592
Muehlan, Clemens; Brooks, Sander; Vaillant, Cedric; Meinel, Michael; Jacobs, Gabriël E; Zuiker, Rob G; Dingemanse, Jasper
发表日期：2022
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Lack of Effect of Cenerimod, a Selective S1P(1) Receptor Modulator, on the Pharmacokinetics of a Combined Oral Contraceptive

选择性S1P(1)受体调节剂Cenerimod对复方口服避孕药药代动力学无影响

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms232314986
Juif, Pierre-Eric; Mueller, Markus S; Charfi, Hakim; Dingemanse, Jasper
信号转导
发表日期：2022
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Single-dose pharmacokinetics, safety, and tolerability of the dual endothelin receptor antagonist aprocitentan in subjects with moderate hepatic impairment

在患有中度肝功能损害的受试者中，单剂量双重内皮素受体拮抗剂阿普西坦的药代动力学、安全性和耐受性研究。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-022-22470-z
Fontes, Magda S C; Dingemanse, Jasper; Halabi, Atef; Tomaszewska-Kiecana, Monika; Sidharta, Patricia N
信号转导
发表日期：2022
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