日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deep sphingolipidomic and metabolomic analyses of ceramide synthase 2 null mice reveal complex pathway-specific effects

对神经酰胺合成酶 2 基因敲除小鼠进行深入的鞘脂组学和代谢组学分析,揭示了复杂的通路特异性效应。

Oh, Jeongah; Muralidharan, Sneha; Zhao, Qing; Scholz, Johannes; Zelnik, Iris D; Blumenreich, Shani; Joseph, Tammar; Dingjan, Tamir; Narayanaswamy, Pradeep; Choi, Hyungwon; Hayen, Heiko; Torta, Federico; Futerman, Anthony H

An anomalous abundance of tryptophan residues in ceramide synthases based on analysis of all membrane proteins in the Swiss-Prot database

基于对Swiss-Prot数据库中所有膜蛋白的分析,发现神经酰胺合成酶中色氨酸残基异常丰富。

Mestre, Beatriz; Zelnik, Iris D; Izrailov, Stav; Dingjan, Tamir; Lvovsky, Gideon; Fidel, Lena; Ben-Dor, Shifra; Futerman, Anthony H

Fine-tuned protein-lipid interactions in biological membranes: exploration and implications of the ORMDL-ceramide negative feedback loop in the endoplasmic reticulum

生物膜中精细调控的蛋白质-脂质相互作用:内质网中ORMDL-神经酰胺负反馈环的探索及其意义

Dingjan, Tamir; Futerman, Anthony H

Computational design and molecular dynamics simulations suggest the mode of substrate binding in ceramide synthases

计算设计和分子动力学模拟表明神经酰胺合酶中的底物结合模式

Iris D Zelnik, Beatriz Mestre, Jonathan J Weinstein, Tamir Dingjan, Stav Izrailov, Shifra Ben-Dor, Sarel J Fleishman, Anthony H Futerman

Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands

抑制一种具有广泛结合能力的GPCR:苦味受体配体的迭代发现

Fierro, Fabrizio; Peri, Lior; Hübner, Harald; Tabor-Schkade, Alina; Waterloo, Lukas; Löber, Stefan; Pfeiffer, Tara; Weikert, Dorothee; Dingjan, Tamir; Margulis, Eitan; Gmeiner, Peter; Niv, Masha Y

Elevation of gangliosides in four brain regions from Parkinson's disease patients with a GBA mutation

帕金森病患者(携带GBA基因突变)四个脑区神经节苷脂水平升高

Blumenreich, Shani; Nehushtan, Tamar; Barav, Or B; Saville, Jennifer T; Dingjan, Tamir; Hardy, John; Fuller, Maria; Futerman, Anthony H

Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma

联合呈现和免疫原性分析揭示黑色素瘤中复发的 RAS.Q61K 新抗原

Aviyah Peri, Erez Greenstein, Michal Alon, Joy A Pai, Tamir Dingjan, Shlomit Reich-Zeliger, Eilon Barnea, Chaya Barbolin, Ronen Levy, Claudia Arnedo-Pac, Shelly Kalaora, Bareket Dassa, Ester Feldmesser, Ping Shang, Polina Greenberg, Yishai Levin, Gil Benedek, Mitchell P Levesque, David J Adams, Mich

NUTM1 is a recurrent fusion gene partner in B-cell precursor acute lymphoblastic leukemia associated with increased expression of genes on chromosome band 10p12.31-12.2

NUTM1 是 B 细胞前体急性淋巴细胞白血病中复发的融合基因伴侣,与 10p12.31-12.2 染色体带上基因表达增加有关

Femke M Hormann, Alex Q Hoogkamer, H Berna Beverloo, Aurélie Boeree, Ilse Dingjan, Moniek M Wattel, Ronald W Stam, Gabriele Escherich, Rob Pieters, Monique L den Boer, Judith M Boer

Human Monocyte-Derived Dendritic Cells Produce Millimolar Concentrations of ROS in Phagosomes Per Second

人类单核细胞衍生的树突状细胞每秒在吞噬体中产生毫摩尔浓度的 ROS

Laurent M Paardekooper, Ilse Dingjan, Peter T A Linders, Alexander H J Staal, Simona M Cristescu, Wilco C E P Verberk, Geert van den Bogaart

The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation

磷酸肌醇激酶 PIKfyve 促进组织蛋白酶 S 介导的主要组织相容性复合物 II 类抗原呈递

Maksim V Baranov, Frans Bianchi, Anastasiya Schirmacher, Melissa A C van Aart, Sjors Maassen, Elke M Muntjewerff, Ilse Dingjan, Martin Ter Beest, Martijn Verdoes, Samantha G L Keyser, Carolyn R Bertozzi, Ulf Diederichsen, Geert van den Bogaart