Removal of a C-terminal serine residue proximal to the inter-chain disulfide bond of a human IgG1 lambda light chain mediates enhanced antibody stability and antibody dependent cell-mediated cytotoxicity
去除人IgG1λ轻链链间二硫键附近的C端丝氨酸残基可增强抗体稳定性和抗体依赖性细胞介导的细胞毒性。
期刊:MAbs
影响因子:5.6
doi:10.4161/mabs.24291
Yang Shen ,Lin Zeng ,Aiping Zhu ,Tim Blanc ,Dipa Patel ,Anthony Pennello ,Amtul Bari ,Stanley Ng ,Kris Persaud ,Yun Kenneth Kang ,Paul Balderes ,David Surguladze ,Sagit Hindi ,Qinwei Zhou ,Dale L Ludwig ,Marshall Snavely
