日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Intrinsic Tumor Aggressiveness Dictates Hypoxia-Driven Metabolic Programs in Hepatocellular Carcinoma

肝细胞癌中肿瘤内在侵袭性决定缺氧驱动的代谢程序

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27073069
Milosa, Fabiola; Giglioli, Nicolò; Critelli, Rosina Maria; Dituri, Francesco; Serino, Grazia; Mancarella, Serena; Villa, Erica
细胞生物学
肿瘤
肿瘤免疫
代谢
发表日期：2026
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Proteoglycan-4 potentiates the antitumor efficacy of regorafenib in an orthotopic model of hepatocellular carcinoma

蛋白聚糖-4可增强瑞戈非尼在原位肝细胞癌模型中的抗肿瘤疗效

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-025-03575-5
Carrieri, Livianna; Munir, Anas; Caragnano, Giusi; Guido, Davide; Serino, Grazia; Piccinno, Emanuele; Mastronardi, Domenico; Bianco, Giusy; Schena, Nicolò; Armentano, Raffaele; Dituri, Francesco; Giannelli, Gianluigi
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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New Experimental Mouse Models to Evaluate the Role of Transforming Growth Factor-Beta in Liver Tumorigenesis

用于评估转化生长因子-β在肝肿瘤发生中作用的新型实验小鼠模型

期刊:Liver International
影响因子:5.2
doi:10.1111/liv.70351
Cantos-Cortes, Ana; Amengual, Josep; Espinosa-Sotelo, Rut; Bertran, Esther; Vaquero, Javier; de Galarreta, Marina Ruiz; Molina-Sanchez, Pedro; Serrano, Teresa; Ramos, Emilio; Calvo, Mariona; Scialpi, Rosanna; Dituri, Francesco; Giannelli, Gianluigi; Lujambio, Amaia; Gonzalez-Sanchez, Ester; Fabregat, Isabel
肿瘤
Mouse
肿瘤免疫
发表日期：2025
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Inhibiting the TGF-β1 Pathway Reduces the Aggressiveness of Intrahepatic CCA HuCCT1 CD90-Positive Cells

抑制TGF-β1通路可降低肝内胆管癌HuCCT1 CD90阳性细胞的侵袭性

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26114973
Pizzuto, Elena; Mancarella, Serena; Gigante, Isabella; Serino, Grazia; Dituri, Francesco; Piccinno, Emanuele; Fabregat, Isabel; Giannelli, Gianluigi
肿瘤
肿瘤免疫
TGF-β
信号转导
CD9
胆管癌
TGF-β1
细胞生物学
CD90
发表日期：2025
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Dual Inhibition of SRC Family Kinases and Sorafenib Enhances Anti-Tumor Activity in Hepatocellular Carcinoma Cells.

SRC家族激酶和索拉非尼的双重抑制增强了肝细胞癌细胞的抗肿瘤活性

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26136506
Cabral Loraine Kay, Disoma Cyrollah, Tarchi Paola, El-Khobar Korri Elvanita, Agustiningsih Agustiningsih, Dituri Francesco, Tiribelli Claudio, Sukowati Caecilia
肿瘤
发表日期：2025
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New Hepatocellular Carcinoma (HCC) Primary Cell Cultures as Models for Exploring Personalized Anti-TGF-β Therapies Based on Tumor Characteristics.

新型肝细胞癌 (HCC) 原代细胞培养物作为基于肿瘤特征探索个性化抗 TGF-β 疗法的模型

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26062430
Scialpi Rosanna, Espinosa-Sotelo Rut, Bertran Esther, Dituri Francesco, Giannelli Gianluigi, Fabregat Isabel
肿瘤
TGF-β
发表日期：2025
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Inorganic Polyphosphate Triggers NLRP3 Inflammasome and Promotes the Epithelial-to-Mesenchymal Transition and Migration of Colorectal Cancer Cells Through TRPM8 Receptor.

无机多聚磷酸盐通过 TRPM8 受体触发 NLRP3 炎症小体，促进结直肠癌细胞的上皮间质转化和迁移

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26167743
Arrè Valentina, Scavo Maria Principia, Donghia Rossella, Dituri Francesco, Mandorino Camilla, Cassotta Marco, Ancona Anna, Balestra Francesco, Vincenti Leonardo, Aquilino Fabrizio, Pettinato Giuseppe, Giannelli Gianluigi, Negro Roberto
细胞生物学
肠癌
炎性小体
炎症
发表日期：2025
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Targeting cancer-associated fibroblasts/tumor cells cross-talk inhibits intrahepatic cholangiocarcinoma progression via cell-cycle arrest

靶向癌相关成纤维细胞/肿瘤细胞间的相互作用可通过细胞周期阻滞抑制肝内胆管癌的进展。

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-024-03210-9
Mancarella, Serena; Gigante, Isabella; Pizzuto, Elena; Serino, Grazia; Terzi, Alberta; Dituri, Francesco; Maiorano, Eugenio; Vincenti, Leonardo; De Bellis, Mario; Ardito, Francesco; Calvisi, Diego F; Giannelli, Gianluigi
成纤维细胞
肿瘤
肿瘤免疫
胆管癌
细胞生物学
肿瘤细胞
发表日期：2024
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Correction: Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models

更正：自泌素抑制剂IOA-289可减缓临床前模型中胃肠道癌症的进展

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-023-02797-9
Centonze, Matteo; Di Conza, Giusy; Lahn, Michael; Fabregat, Isabel; Dituri, Francesco; Gigante, Isabella; Serino, Grazia; Scialpi, Rosanna; Carrieri, Livianna; Negro, Roberto; Pizzuto, Elena; Giannelli, Gianluigi
肿瘤
肿瘤免疫
发表日期：2023
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PD-L1 Downregulation and DNA Methylation Inhibition for Molecular Therapy against Cancer Stem Cells in Hepatocellular Carcinoma

PD-L1下调和DNA甲基化抑制在肝细胞癌癌症干细胞分子治疗中的应用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms241713357
Sukowati, Caecilia; Cabral, Loraine Kay D; Anfuso, Beatrice; Dituri, Francesco; Negro, Roberto; Giannelli, Gianluigi; Tiribelli, Claudio
肿瘤
表观遗传
肿瘤免疫
细胞生物学
DNA甲基化
PD-L1
干细胞
DNA甲基化
发育与干细胞
发表日期：2023
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