日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bi-specific T cell-engaging antibody triggers protective immune memory and glioma microenvironment remodeling in immune-competent preclinical models

双特异性T细胞结合抗体在免疫功能健全的临床前模型中诱导保护性免疫记忆和胶质瘤微环境重塑

Markella Zannikou # ,Joseph T Duffy # ,Daniele Procissi ,Hinda Najem ,Rebecca N Levine ,Aditi Thakur ,Dolores Hambardzumyan ,Catalina Lee-Chang ,Lara Leoni ,Craig M Horbinski ,Dmitri Simberg ,Bin Zhang ,Amy B Heimberger ,Jason Miska ,Irina V Balyasnikova

Nanoparticle-Binding Immunoglobulins Predict Variable Complement Responses in Healthy and Diseased Cohorts

纳米颗粒结合免疫球蛋白可预测健康和患病人群中不同的补体反应

Yue Li, Laura Saba, Robert I Scheinman, Nirmal K Banda, Michael Holers, Andrew Monte, Layne Dylla, S Moein Moghimi, Dmitri Simberg

Antibody-Dependent Complement Responses toward SARS-CoV-2 Receptor-Binding Domain Immobilized on "Pseudovirus-like" Nanoparticles

针对固定在“假病毒样”纳米颗粒上的SARS-CoV-2受体结合域的抗体依赖性补体反应

Hanmant Gaikwad ,Yue Li, Guankui Wang ,Ronghui Li, Shaodong Dai, Cody Rester ,Ross Kedl ,Laura Saba, Nirmal K Banda ,Robert I Scheinman ,Casey Patrick, Krishna M G Mallela, S Moein Moghimi ,Dmitri Simberg

PEGylated Liposomes Accumulate in the Areas Relevant to Skin Toxicities via Passive Extravasation across "Leaky" Endothelium

聚乙二醇化脂质体通过“渗漏”内皮的被动外渗作用,在与皮肤毒性相关的区域积聚。

Yue Li, Laren Lofchy, Guankui Wang, Hanmant Gaikwad, Mayumi Fujita, Dmitri Simberg

Indocarbocyanine nanoparticles extravasate and distribute better than liposomes in brain tumors

吲哚羰菁纳米粒子在脑肿瘤中的渗出和分布比脂质体更好

Irina V Balyasnikova, Markella Zannikou, Guankui Wang, Yue Li, Joseph T Duffy, Rebecca N Levine, Maggie Seblani, Hanmant Gaikwad, Dmitri Simberg

Highly aminated iron oxide nanoworms for simultaneous manufacturing and labeling of chimeric antigen receptor T cells

高度胺化的氧化铁纳米蠕虫用于同时制造和标记嵌合抗原受体 T 细胞

Wei Zhang, Hanmant Gaikwad, Ernest V Groman, Enkhtsetseg Purev, Dmitri Simberg, Guankui Wang

Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking

树枝状聚合物末端基序依赖性逃避人类补体和通过 IgM 搭便车补体激活

Lin-Ping Wu, Mario Ficker, Jørn B Christensen, Dmitri Simberg, Panagiotis N Trohopoulos, Seyed M Moghimi

Complement opsonization of nanoparticles: Differences between humans and preclinical species

纳米粒子的补体调理作用:人类与临床前物种之间的差异

Yue Li, Guankui Wang, Lynn Griffin, Nirmal K Banda, Laura M Saba, Ernest V Groman, Robert Scheinman, S Moein Moghimi, Dmitri Simberg

Lipid nanoparticle formulation of niclosamide (nano NCM) effectively inhibits SARS-CoV-2 replication in vitro

氯硝柳胺脂质纳米颗粒制剂(纳米 NCM)可有效抑制体外 SARS-CoV-2 复制

Guankui Wang #, Hanmant Gaikwad #, Mary K McCarthy, Mercedes Gonzalez-Juarrero, Yue Li, Michael Armstrong, Nichole Reisdorph, Thomas E Morrison, Dmitri Simberg

Delivery of a model lipophilic membrane cargo to bone marrow via cell-derived microparticles

通过细胞衍生微粒将模型亲脂性膜载荷递送至骨髓

Chunyan Yang ,Fangfang Chen ,Ping Ren ,Laren Lofchy ,Chun Wan ,Jingshi Shen ,Guankui Wang ,Hanmant Gaikwad ,Jessica Ponder ,Craig T Jordan ,Robert Scheinman ,Dmitri Simberg