日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel Anti-Melanoma Compounds Are Efficacious in A375 Cell Line Xenograft Melanoma Model in Nude Mice

新型抗黑色素瘤化合物对裸鼠 A375 细胞系异种移植黑色素瘤模型有效

Sadeeshkumar Velayutham, Ryan Seerattan, Maab Sultan, Trisha Seal, Samaya Danthurthy, Baskaran Chinnappan, Jessica Landi, Kaitlyn Pearl, Aveta Singh, Keiran S M Smalley, Julia Zaias, Jun Yong Choi, Dmitriy Minond

Mucin-Type O-Glycosylation Proximal to β-Secretase Cleavage Site Affects APP Processing and Aggregation Fate

β-分泌酶裂解位点附近的粘蛋白型 O-糖基化影响 APP 加工和聚集命运

YashoNandini Singh, Deepika Regmi, David Ormaza, Ramya Ayyalasomayajula, Nancy Vela, Gustavo Mundim, Deguo Du, Dmitriy Minond, Maré Cudic

In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators

计算机模拟和实验 ADAM17 动力学建模作为未来调节剂筛选系统的基础

Marian Bienstein, Dmitriy Minond, Ulrich Schwaneberg, Mehdi D Davari, Daniela Yildiz

Tyrosine O-GalNAc Alters the Conformation and Proteolytic Susceptibility of APP Model Glycopeptides

酪氨酸 O-GalNAc 改变 APP 模型糖肽的构象和蛋白水解敏感性

YashoNandini Singh, David Ormaza, Alessandra Massetti, Dmitriy Minond, Maré Cudic

Discovery and Optimization of Selective Inhibitors of Meprin α (Part II)

Meprin α 选择性抑制剂的发现与优化(第二部分)

Chao Wang, Juan Diez, Hajeung Park, Timothy P Spicer, Louis D Scampavia, Christoph Becker-Pauly, Gregg B Fields, Dmitriy Minond, Thomas D Bannister

Discovery and Optimization of Selective Inhibitors of Meprin α (Part I)

Meprin α 选择性抑制剂的发现与优化(第一部分)

Shurong Hou, Juan Diez, Chao Wang, Christoph Becker-Pauly, Gregg B Fields, Thomas Bannister, Timothy P Spicer, Louis D Scampavia, Dmitriy Minond

A Novel Probe for Spliceosomal Proteins that Induces Autophagy and Death of Melanoma Cells Reveals New Targets for Melanoma Drug Discovery

诱导黑色素瘤细胞自噬和死亡的剪接体蛋白新型探针揭示了黑色素瘤药物研发的新靶点

Manikandan Palrasu, Anna M Knapinska, Juan Diez, Lyndsay Smith, Travis LaVoi, Marc Giulianotti, Richard A Houghten, Gregg B Fields, Dmitriy Minond

Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide

恒河猴θ-防御素-1(一种免疫调节大环肽)抑制和消退自身免疫性关节炎

Justin B Schaal, Dat Q Tran, Akshay Subramanian, Reshma Patel, Teresina Laragione, Kevin D Roberts, Katie Trinh, Prasad Tongaonkar, Patti A Tran, Dmitriy Minond, Gregg B Fields, Paul Beringer, André J Ouellette, Percio S Gulko, Michael E Selsted

Discovery of an enzyme and substrate selective inhibitor of ADAM10 using an exosite-binding glycosylated substrate

利用外部位点结合糖基化底物发现 ADAM10 的酶和底物选择性抑制剂

Franck Madoux, Daniela Dreymuller, Jean-Phillipe Pettiloud, Radleigh Santos, Christoph Becker-Pauly, Andreas Ludwig, Gregg B Fields, Thomas Bannister, Timothy P Spicer, Mare Cudic, Louis D Scampavia, Dmitriy Minond

SAR Studies of Exosite-Binding Substrate-Selective Inhibitors of A Disintegrin And Metalloprotease 17 (ADAM17) and Application as Selective in Vitro Probes

解整合素和金属蛋白酶 17 (ADAM17) 的外部位点结合底物选择性抑制剂的 SAR 研究及其作为选择性体外探针的应用

Anna M Knapinska, Daniela Dreymuller, Andreas Ludwig, Lyndsay Smith, Vladislav Golubkov, Anjum Sohail, Rafael Fridman, Marc Giulianotti, Travis M LaVoi, Richard A Houghten, Gregg B Fields, Dmitriy Minond