日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-cell analysis identifies Ifi27l2a as a gene regulator of microglial inflammation in the context of aging and stroke in mice.

单细胞分析发现 Ifi27l2a 是小鼠衰老和中风背景下小胶质细胞炎症的基因调节因子

Kim Gab Seok, Harmon Elisabeth, Gutierrez Manuel C, Kim Sodam, Vance Lauren, Burrous Haven, Stephenson Jessica M, Chauhan Anjali, Banerjee Anik, Wise Zachary, Doan Andrea, Ahn John, Wu Ting, Bautista-Garrido Jesus, Lee Juneyoung, Tan Chunfeng, Jung Joo Eun, McCullough Louise D, Wythe Joshua D, Marrelli Sean P

Peritoneal delivery of capsinoids, nonpungent TRPV1 agonists, induces mild hypothermia in conscious mice through TRPV1 activation of visceral vagal afferents

腹膜注射辣椒素类物质(一种非刺激性的TRPV1激动剂)可通过TRPV1激活内脏迷走神经传入纤维,在清醒小鼠中诱发轻度体温过低。

Andersohn, Alexander P; Wu, Ting; Doan, Andrea N; Cantrell, Charles L; Jarret, Robert L; Marrelli, Sean P

Ifi27l2a acts as a cytokine that promotes a pro-inflammatory phenotype in microglia and enhances neuroinflammation.

Ifi27l2a 作为一种细胞因子,可促进小胶质细胞的促炎表型,并增强神经炎症。

Kim Sodam, Burrous Haven, Harmon Elisabeth, Vance Lauren, Wu Ting, Andersohn Alexander, Doan Andrea, Wolocko Darby, Wise Zachary, Kitamura Yuki, Jung Joo Eun, Colpo Gabriela, Couture Lucy, Blixt Frank, McCullough Louise, Marrelli Sean, Kim Gab Seok

Single-cell analysis identifies Ifi27l2a as a novel gene regulator of microglial inflammation in the context of aging and stroke.

单细胞分析发现 Ifi27l2a 是衰老和中风背景下小胶质细胞炎症的新型基因调节因子

Kim Gab Seok, Harmon Elisabeth, Gutierrez Manuel, Stephenson Jessica, Chauhan Anjali, Banerjee Anik, Wise Zachary, Doan Andrea, Wu Ting, Lee Juneyoung, Jung Joo Eun, McCullough Louise, Wythe Joshua, Marrelli Sean