日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells.

同时靶向 KRAS 和 CDK4 可协同诱导胰腺癌细胞持久生长停滞。

Paulsohn Maj-Britt, Frahnert Klara Henrike, Schlösser Denise, Oschwald Joana, Kopp Waltraut, Fang Xin, Schneider Carolin, Tapia Contreras Constanza, Danieli-Mackay Adi, Ludewig Fabian, Bleyer Martina, Salinas Gabriela, Schneider Günter, Hessmann Elisabeth, Dobbelstein Matthias

Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro.

p63 的 DBD 连接区中的选择性剪接可调节其在体外与 DNA 和 iASPP 的结合

Lotz Rebecca, Osterburg Christian, Chaikuad Apirat, Weber Sabrina, Akutsu Masato, Machel Anne Christin, Beyer Ulrike, Gebel Jakob, Löhr Frank, Knapp Stefan, Dobbelstein Matthias, Lu Xin, Dötsch Volker

Synergistic activity of RSL3 and Pyrimethamine to inhibit the proliferation of Plasmodium falciparum

RSL3 和乙胺嘧啶对抑制恶性疟原虫增殖具有协同作用

Nikolova, Vella; Linnemannstöns, Karen; Zahoruiko, Anastasiia; Ganter, Markus; Lüder, Carsten G; Dobbelstein, Matthias

Myricetin-bound crystal structure of the SARS-CoV-2 helicase NSP13 facilitates the discovery of novel natural inhibitors.

SARS-CoV-2 解旋酶 NSP13 与杨梅素结合的晶体结构有助于发现新型天然抑制剂

Kloskowski Patrick, Neumann Piotr, Kumar Priya, Berndt Annette, Dobbelstein Matthias, Ficner Ralf

Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies.

利用高效、超耐热、耐突变的纳米抗体中和 SARS-CoV-2

Güttler Thomas, Aksu Metin, Dickmanns Antje, Stegmann Kim M, Gregor Kathrin, Rees Renate, Taxer Waltraud, Rymarenko Oleh, Schünemann Jürgen, Dienemann Christian, Gunkel Philip, Mussil Bianka, Krull Jens, Teichmann Ulrike, Groß Uwe, Cordes Volker C, Dobbelstein Matthias, Görlich Dirk

SO-1 The impact of COVID-19 on daily practice patterns in the third-line setting for patients with metastatic colorectal cancer: Results of a real-world survey

SO-1 COVID-19 对转移性结直肠癌患者三线治疗日常实践模式的影响:一项真实世界调查的结果

Güttler, Thomas; Dobbelstein, Matthias; Görlich, Dirk; Xanthouli, Panagiota; Prager, G; Köhne, C; O’Connor, J; Rivera Herrero, F; Santini, D; Wasan, H; Phelip, J

Correction: The integrated stress response induces R-loops and hinders replication fork progression

更正:整合应激反应会诱导R环形成并阻碍复制叉的延伸。

Choo, Josephine Ann Mun Yee; Schlösser, Denise; Manzini, Valentina; Magerhans, Anna; Dobbelstein, Matthias

Mdm2: Open questions

Mdm2:未解决的问题

Dobbelstein, Matthias; Levine, Arnold J

Correction: Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells

更正:DNA交联与HSP90抑制之间强大的抗肿瘤协同作用导致卵巢癌细胞中大量有丝分裂前DNA片段化。

Kramer, Daniela; Stark, Nadine; Schulz-Heddergott, Ramona; Erytch, Norman; Edmunds, Shelley; Roßmann, Laura; Bastians, Holger; Concin, Nicole; Moll, Ute M; Dobbelstein, Matthias

Chromatin modifiers Mdm2 and RNF2 prevent RNA:DNA hybrids that impair DNA replication

染色质修饰因子Mdm2和RNF2可防止RNA:DNA杂交体的形成,从而避免DNA复制受损。

Klusmann, Ina; Wohlberedt, Kai; Magerhans, Anna; Teloni, Federico; Korbel, Jan O; Altmeyer, Matthias; Dobbelstein, Matthias