Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrotaline
激活素样激酶5 (ALK5) 介导家族性肺动脉高压患者血管平滑肌细胞的异常增殖,并参与单克罗他林诱导的实验性肺动脉高压的进展。
期刊:American Journal of Pathology
影响因子:3.6
doi:10.2353/ajpath.2009.080565
Thomas, Matthew; Docx, Cerys; Holmes, Alan M; Beach, Sarah; Duggan, Nicholas; England, Karen; Leblanc, Catherine; Lebret, Clemence; Schindler, Francis; Raza, Farheen; Walker, Christoph; Crosby, Alexi; Davies, Rachel J; Morrell, Nicholas W; Budd, David C