日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preeclampsia risk prediction from prenatal cell-free DNA screening

利用产前无细胞DNA筛查预测先兆子痫风险

Adil, Mohamed; Kolarova, Teodora R; Doebley, Anna-Lisa; Chen, Leah A; Tobey, Cara L; Galipeau, Patricia; Rosen, Sam; Yang, Michael; Colbert, Brice; Patton, Robert D; Persse, Thomas W; Kawelo, Erin; Reichel, Jonathan B; Pritchard, Colin C; Akilesh, Shreeram; Lockwood, Christina M; Ha, Gavin; Shree, Raj

Hypophagia and body weight loss by tirzepatide are accompanied by fewer GI adverse events compared to semaglutide in preclinical models.

在临床前模型中,与司美格鲁肽相比,替拉帕肽引起的食欲减退和体重减轻伴随的胃肠道不良事件较少

Borner Tito, Pataro Allison M, Doebley Sarah A, Furst Charles D, White Alex D, Gao Serena X, Chow Angela, Sanchez-Navarro Marcos J, Ghidewon Misgana Y, Halas Julia G, Mohiby Allaha Z, Willard Francis S, Grill Harvey J, Ai Minrong, Samms Ricardo J, Hayes Matthew R, De Jonghe Bart C

Molecular phenotyping of small cell lung cancer using targeted cfDNA profiling of transcriptional regulatory regions

利用靶向cfDNA转录调控区域谱分析对小细胞肺癌进行分子表型分析

Joseph B Hiatt ,Anna-Lisa Doebley ,Henry U Arnold ,Mohamed Adil ,Holly Sandborg ,Thomas W Persse ,Minjeong Ko ,Feinan Wu ,Alvaro Quintanal Villalonga ,Rafael Santana-Davila ,Keith Eaton ,Caroline Dive ,Charles M Rudin ,Anish Thomas ,A McGarry Houghton ,Gavin Ha ,David MacPherson

Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes.

循环肿瘤DNA中的核小体模式揭示了晚期前列腺癌表型的转录调控

De Sarkar Navonil, Patton Robert D, Doebley Anna-Lisa, Hanratty Brian, Adil Mohamed, Kreitzman Adam J, Sarthy Jay F, Ko Minjeong, Brahma Sandipan, Meers Michael P, Janssens Derek H, Ang Lisa S, Coleman Ilsa M, Bose Arnab, Dumpit Ruth F, Lucas Jared M, Nunez Talina A, Nguyen Holly M, McClure Heather M, Pritchard Colin C, Schweizer Michael T, Morrissey Colm, Choudhury Atish D, Baca Sylvan C, Berchuck Jacob E, Freedman Matthew L, Ahmad Kami, Haffner Michael C, Montgomery R Bruce, Corey Eva, Henikoff Steven, Nelson Peter S, Ha Gavin

Creation of a Peptide Antagonist of the GFRAL-RET Receptor Complex for the Treatment of GDF15-Induced Malaise

构建GFRAL-RET受体复合物肽拮抗剂用于治疗GDF15诱导的不适

Tito Borner ,Ian C Tinsley ,Brandon T Milliken ,Sarah A Doebley ,Nicholas R Najjar ,Deborah J Kerwood ,Bart C De Jonghe ,Matthew R Hayes ,Robert P Doyle

GIP receptor agonism blocks chemotherapy-induced nausea and vomiting

GIP受体激动剂可阻断化疗引起的恶心和呕吐

Borner, Tito; Reiner, Benjamin C; Crist, Richard C; Furst, C Daniel; Doebley, Sarah A; Halas, Julia G; Ai, Minrong; Samms, Ricardo J; De Jonghe, Bart C; Hayes, Matthew R

Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effects

限制外周催产素足以减少食物摄入和动机,而运动和味觉回避效应则需要中枢神经系统进入

Mohammed Asker, Jean-Philippe Krieger, Amber Liles, Ian C Tinsley, Tito Borner, Ivana Maric, Sarah Doebley, C Daniel Furst, Stina Börchers, Francesco Longo, Yashaswini R Bhat, Bart C De Jonghe, Matthew R Hayes, Robert P Doyle, Karolina P Skibicka

Screening study of anti-emetics to improve GDF15-induced malaise and anorexia: Implications for emesis control

止吐药改善 GDF15 引起的不适和厌食症的筛选研究:对呕吐控制的启示

Tito Borner, Sarah A Doebley, C Daniel Furst, Allison M Pataro, Julia G Halas, Xing Gao, Grace K Choi, Sarah A Ramadan, Angela Chow, Bart C De Jonghe

A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA

根据游离 DNA 核小体分析建立临床癌症亚型分析框架

Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A Eden Cruikshank, Katheryn Santos, Caroline Kikawa, Joseph B Hiatt, Robert D Patton, Navonil De Sarkar, Katharine A Collier, Anna C H Hoge, Katharine Chen, Anat Zimmer, Zachary T Weber, Mohamed Adil, Jonathan B Reichel, Paz Polak, Viktor A Adalsteinsson, 

Hypophagia induced by salmon calcitonin, but not by amylin, is partially driven by malaise and is mediated by CGRP neurons

鲑鱼降钙素引起的吞咽功能减退,而非胰淀素引起的吞咽功能减退,部分是由不适引起的,并由 CGRP 神经元介导

Lavinia Boccia, Tito Borner, Misgana Y Ghidewon, Patricia Kulka, Chiara Piffaretti, Sarah A Doebley, Bart C De Jonghe, Harvey J Grill, Thomas A Lutz, Christelle Le Foll