日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stress vesicles link epidermal mechanotransduction to stem cell differentiation.

应力囊泡将表皮力学传导与干细胞分化联系起来。

Huang Sixia, Kuri Paola, Zou Jonathan, Blanco Adriana, Marshall Maxwell, Rice Gabriella, Prouty Stephen, Dentchev Tzvete, Doepner Miriam, Boerckel Joel D, Capell Brian C, Ridky Todd W, Rompolas Panteleimon

Varicella-zoster virus reactivation and the risk of dementia

水痘-带状疱疹病毒再激活与痴呆风险

Polisky, Vitaly; Littmann, Maria; Triastcyn, Aleksei; Horn, Max; Georgiou, Andreas; Widenmaier, Robyn; Anspach, Bruno; Tahrat, Halima; Kumar, Sanjay; Buser-Doepner, Carolyn; Geldsetzer, Pascal; Van Duijn, Cornelia M; Schwab, Patrick

Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health

基于全基因组测序的群体规模基因分析能够深入了解代谢健康。

Zhao, Yajie; Lockhart, Sam; Liu, Jimmy; Li, Xihao; Cortes, Adrian; Hua, Xing; Gardner, Eugene J; Kentistou, Katherine A; Cañadas-Garre, Marisa; Fabian, Laurie; Ho, Karen; Timpson, Nicholas; Lo, Yancy; Davitte, Jonathan; Savage, David B; Buser-Doepner, Carolyn; Ong, Ken K; Zhang, Haoyu; Scott, Robert; O'Rahilly, Stephen; Perry, John R B

LNS8801 inhibits Acute Myeloid Leukemia by Inducing the Production of Reactive Oxygen Species and Activating the Endoplasmic Reticulum Stress Pathway

LNS8801 通过诱导活性氧的产生和激活内质网应激通路来抑制急性髓系白血病

Inyoung Lee, Miriam Doepner, Jillian Weissenrieder, Ariana D Majer, Sophia Mercado, Angela Estell, Christopher A Natale, Pamela J Sung, J Kevin Foskett, Martin P Carroll, Todd W Ridky

Targeting anti-apoptotic pathways eliminates senescent melanocytes and leads to nevi regression

靶向抗凋亡途径可消除衰老的黑素细胞并导致痣消退

Jaskaren Kohli, Chen Ge, Eleni Fitsiou, Miriam Doepner, Simone M Brandenburg, William J Faller, Todd W Ridky, Marco Demaria

Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer

Bcl-xL 强制实现胰腺癌在营养缺乏的微环境中生存所必需的慢循环状态

Yogev Sela #, Jinyang Li #, Shivahamy Maheswaran, Robert Norgard, Salina Yuan, Maimon Hubbi, Miriam Doepner, Jimmy P Xu, Elaine S Ho, Clementina Mesaros, Colin Sheehan, Grace Croley, Alexander Muir, Ian A Blair, Ophir Shalem, Chi V Dang, Ben Z Stanger

Endogenous DOPA inhibits melanoma through suppression of CHRM1 signaling

内源性多巴胺通过抑制 CHRM1 信号抑制黑色素瘤

Miriam Doepner, Inyoung Lee, Christopher A Natale, Roderick Brathwaite, Swati Venkat, Sung Hoon Kim, Yiliang Wei, Christopher R Vakoc, Brian C Capell, John A Katzenellenbogen, Benita S Katzenellenbogen, Michael E Feigin, Todd W Ridky

Osteo-Proliferative Lesions of the Phalanges on Radiography: Associations with Sex, Age, and Osteoarthritis

放射影像学上的指骨增生性病变:与性别、年龄和骨关节炎的关系

Hermann, Sandra; Eshed, Iris; Sáenz, Iván; Doepner, Niclas; Ziegeler, Katharina; Hermann, Kay Geert A

Somatic structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma

体细胞结构变异靶向神经发育基因,并确定 SHANK2 是神经母细胞瘤的肿瘤抑制因子

Gonzalo Lopez #, Karina L Conkrite #, Miriam Doepner, Komal S Rathi, Apexa Modi, Zalman Vaksman, Lance M Farra, Eric Hyson, Moataz Noureddine, Jun S Wei, Malcolm A Smith, Shahab Asgharzadeh, Robert C Seeger, Javed Khan, Jaime Guidry Auvil, Daniela S Gerhard, John M Maris, Sharon J Diskin

The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination

BRISC 去泛素化酶复合物通过调节 JAK2 K63 泛素化来限制造血干细胞扩增

Ryan Donaghy, Xu Han, Krasimira Rozenova, Kaosheng Lv, Qinqin Jiang, Miriam Doepner, Roger A Greenberg, Wei Tong