日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A superantigen-based MHC class II-targeted cancer immunotherapy for the treatment of acute myeloid leukemia

一种基于超抗原的靶向MHC II类分子的癌症免疫疗法用于治疗急性髓系白血病

Lena Golick ,Reeder M Robinson ,Leticia Reyes ,Nadia St Thomas ,Kathleen Klinzing ,Erin C O'Connor ,Leonardo M R Ferreira ,Nathan G Dolloff

Pharmacological Modulation of the Unfolded Protein Response as a Therapeutic Approach in Cutaneous T-Cell Lymphoma

药物调节未折叠蛋白反应作为皮肤 T 细胞淋巴瘤的治疗方法

Nadia St Thomas, Benjamin N Christopher, Leticia Reyes, Reeder M Robinson, Lena Golick, Xiaoyi Zhu, Eli Chapman, Nathan G Dolloff

Modulating the CXCR2 Signaling Axis Using Engineered Chemokine Fusion Proteins to Disrupt Myeloid Cell Infiltration in Pancreatic Cancer

利用工程化趋化因子融合蛋白调节CXCR2信号通路以破坏胰腺癌中的髓系细胞浸润

Benjamin N Christopher ,Lena Golick ,Ashton Basar ,Leticia Reyes ,Reeder M Robinson ,Aaron O Angerstein ,Carsten Krieg ,G Aaron Hobbs ,Denis C Guttridge ,John P O'Bryan ,Nathan G Dolloff

A High-Affinity Monoclonal Antibody Against the Pancreatic Ductal Adenocarcinoma Target, Anterior Gradient-2 (AGR2/PDIA17)

针对胰腺导管腺癌靶点、前梯度-2(AGR2/PDIA17)的高亲和力单克隆抗体

Reeder M Robinson, Leticia Reyes, Benjamin N Christopher, Ravyn M Duncan, Rachel A Burge, Julie Siegel, Patrick Nasarre, Pingping Wang, John P O'Bryan, G Aaron Hobbs, Nancy Klauber-DeMore, Nathan G Dolloff

Stimulation of natural killer cells with small molecule inhibitors of CD38 for the treatment of neuroblastoma

利用 CD38 小分子抑制剂刺激自然杀伤细胞治疗神经母细胞瘤

Catherine M Mills, Thomas Z Benton, Ivett Piña, Megan J Francis, Leticia Reyes, Nathan G Dolloff, Yuri K Peterson, Patrick M Woster

Secreted frizzled related-protein 2 is prognostic for human pancreatic cancer patient survival and is associated with fibrosis

分泌型卷曲相关蛋白 2 可预测人类胰腺癌患者的生存情况,并与纤维化有关

Julie B Siegel, Patrick Nasarre, Lillian Hsu, Rupak Mukherjee, Meghan Gormley, Bailey Richardson, Imran Khan, Jordan E Morningstar, Eleanor Hilliard, John P O'Bryan, Kristi L Helke, Laura Spruill, Nathan G Dolloff, Nancy Klauber-DeMore

PDI inhibitor LTI6426 enhances panobinostat efficacy in preclinical models of multiple myeloma

PDI 抑制剂 LTI6426 增强了帕比司他在多发性骨髓瘤临床前模型中的疗效

Reeder M Robinson, Ashton P Basar, Leticia Reyes, Ravyn M Duncan, Hong Li, Nathan G Dolloff

Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation

选择性靶向CD38水解酶和环化酶活性作为免疫刺激的一种方法

Benton, Thomas Z; Mills, Catherine M; Turner, Jonathan M; Francis, Megan J; Solomon, Dalan J; Burger, Pieter B; Peterson, Yuri K; Dolloff, Nathan G; Bachmann, André S; Woster, Patrick M

ATF3 Coordinates Antitumor Synergy between Epigenetic Drugs and Protein Disulfide Isomerase Inhibitors

ATF3 协调表观遗传药物和蛋白质二硫键异构酶抑制剂之间的抗肿瘤协同作用

Ravyn M Duncan ,Leticia Reyes ,Katelyn Moats ,Reeder M Robinson ,Sara A Murphy ,Balveen Kaur ,Holly A F Stessman ,Nathan G Dolloff

Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity

基于帕比司他设计的含酰肼的HDACI及其抗白血病活性的p53和FLT3-ITD依赖性

Xiaoyang Li, Yuqi Jiang, Yuri K Peterson, Tongqiang Xu, Richard A Himes, Xin Luo, Guilin Yin, Elizabeth S Inks, Nathan Dolloff, Stephanie Halene, Sherine S L Chan, C James Chou