日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

KCTD Proteins Have Redundant Functions in Controlling Cellular Growth

KCTD 蛋白在控制细胞生长方面具有冗余功能

Robert Rizk, Dominic Devost, Darlaine Pétrin, Terence E Hébert

Structure and dynamics of a pentameric KCTD5/CUL3/Gβγ E3 ubiquitin ligase complex

五聚体 KCTD5/CUL3/Gβγ E3 泛素连接酶复合物的结构和动力学

Duc Minh Nguyen, Deanna H Rath, Dominic Devost, Darlaine Pétrin, Robert Rizk, Alan X Ji, Naveen Narayanan, Darren Yong, Andrew Zhai, Douglas A Kuntz, Maha U Q Mian, Neil C Pomroy, Alexander F A Keszei, Samir Benlekbir, Mohammad T Mazhab-Jafari, John L Rubinstein, Terence E Hébert, Gilbert G Privé

The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization

孤儿 G 蛋白偶联受体 GPR52 是乳腺癌多细胞组织的新型调节剂

Sarah Z Hanif, CheukMan Cherie Au, Ingrid Torregroza, Syeda Y Jannath, Tabassum Fabiha, Bhavneet Bhinder, Michael Washburn, Dominic Devost, Shuchen Liu, Priya Bhardwaj, Todd Evans, Pradeep Kumar Anand, Robert Tarran, Sailesh Palikhe, Olivier Elemento, Lukas Dow, John Blenis, Terence E Hébert, Kristy

Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody

合成胞内抗体对 GPCR 诱导的 β-arrestin 运输和信号传导的变构调节

Mithu Baidya #, Madhu Chaturvedi #, Hemlata Dwivedi-Agnihotri #, Ashutosh Ranjan, Dominic Devost, Yoon Namkung, Tomasz Maciej Stepniewski, Shubhi Pandey, Minakshi Baruah, Bhanupriya Panigrahi, Parishmita Sarma, Manish K Yadav, Jagannath Maharana, Ramanuj Banerjee, Kouki Kawakami, Asuka Inoue, Jana S

IBD-associated G protein-coupled receptor 65 variant compromises signalling and impairs key functions involved in inflammation

IBD 相关 G 蛋白偶联受体 65 变体损害信号传导并削弱与炎症有关的关键功能

Virginie Mercier, Gabrielle Boucher, Dominic Devost, Kyla Bourque, Azadeh Alikashani, Claudine Beauchamp, Alain Bitton, Sylvain Foisy, Philippe Goyette, Guy Charron, Terence E Hébert, John D Rioux

Addition of a carboxy-terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice

在通常无尾的促性腺激素释放激素受体上添加羧基末端尾巴会损害雌性小鼠的生育能力

Chirine Toufaily, Jérôme Fortin, Carlos Ai Alonso, Evelyne Lapointe, Xiang Zhou, Yorgui Santiago-Andres, Yeu-Farn Lin, Yiming Cui, Ying Wang, Dominic Devost, Ferdinand Roelfsema, Frederik Steyn, Aylin C Hanyaloglu, Terence E Hébert, Tatiana Fiordelisio, Derek Boerboom, Daniel J Bernard

Asymmetric Recruitment of β-Arrestin1/2 by the Angiotensin II Type I and Prostaglandin F2α Receptor Dimer

血管紧张素 II I 型和前列腺素 F2α 受体二聚体对 β-Arrestin1/2 的不对称募集

Dany Fillion, Dominic Devost, Rory Sleno, Asuka Inoue, Terence E Hébert

BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes

基于 BRET 的检测方法监测 AT1R 对 EGFR 的转录激活,结果显示 Gq/11 蛋白非依赖性激活和 AT1R-EGFR 复合物

Shannon L O'Brien, Elizabeth K M Johnstone, Dominic Devost, Jacinta Conroy, Melissa E Reichelt, Brooke W Purdue, Mohammed A Ayoub, Tatsuo Kawai, Asuka Inoue, Satoru Eguchi, Terence E Hébert, Kevin D G Pfleger, Walter G Thomas

Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors

使用通路范围的 BRET 信号传感器对血管紧张素 II 1 型受体进行功能选择性分析

Yoon Namkung, Christian LeGouill, Sahil Kumar, Yubo Cao, Larissa B Teixeira, Viktoriya Lukasheva, Jenna Giubilaro, Sarah C Simões, Jean-Michel Longpré, Dominic Devost, Terence E Hébert, Graciela Piñeyro, Richard Leduc, Claudio M Costa-Neto, Michel Bouvier, Stéphane A Laporte

Conformational biosensors reveal allosteric interactions between heterodimeric AT1 angiotensin and prostaglandin F2α receptors

构象生物传感器揭示异二聚体 AT1 血管紧张素和前列腺素 F2α 受体之间的变构相互作用

Rory Sleno, Dominic Devost, Darlaine Pétrin, Alice Zhang, Kyla Bourque, Yuji Shinjo, Junken Aoki, Asuka Inoue, Terence E Hébert