日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund's adjuvant-induced paw inflammation model

在 aP2 启动子的控制下,过量表达人类 ALOX15 的转基因小鼠在完全弗氏佐剂诱发的爪炎症模型中受到部分保护

Dagmar Heydeck, Kumar R Kakularam, Dominika Labuz, Halina Machelska, Nadine Rohwer, Karsten Weylandt, Hartmut Kuhn

Humanization of the Reaction Specificity of Mouse Alox15b Inversely Modified the Susceptibility of Corresponding Knock-In Mice in Two Different Animal Inflammation Models

小鼠 Alox15b 反应特异性的人源化反向改变了相应基因敲入小鼠在两种不同动物炎症模型中的易感性

Marjann Schäfer, Florian Reisch, Dominika Labuz, Halina Machelska, Sabine Stehling, Gerhard P Püschel, Michael Rothe, Dagmar Heydeck, Hartmut Kuhn

Interleukin-4 Induces the Release of Opioid Peptides from M1 Macrophages in Pathological Pain

白细胞介素-4 诱导病理疼痛中 M1 巨噬细胞释放阿片肽

Dominika Labuz, Melih Ö Celik, Viola Seitz, Halina Machelska

Knock-In Mice Expressing a 15-Lipoxygenating Alox5 Mutant Respond Differently to Experimental Inflammation Than Reported Alox5-/- Mice

表达 15-脂氧合 Alox5 突变体的基因敲入小鼠对实验性炎症的反应与已报道的 Alox5-/- 小鼠不同

Eugenia Marbach-Breitrück, Nadine Rohwer, Carmen Infante-Duarte, Silvina Romero-Suarez, Dominika Labuz, Halina Machelska, Laura Kutzner, Nils Helge Schebb, Michael Rothe, Pallu Reddanna, Karsten H Weylandt, Lothar H Wieler, Dagmar Heydeck, Hartmut Kuhn

IL-4 induces M2 macrophages to produce sustained analgesia via opioids

IL-4 通过阿片类药物诱导 M2 巨噬细胞产生持续镇痛作用

Melih Ö Celik, Dominika Labuz, Jacqueline Keye, Rainer Glauben, Halina Machelska

Mu-Opioid Receptor Agonist Induces Kir3 Currents in Mouse Peripheral Sensory Neurons - Effects of Nerve Injury

Mu-阿片受体激动剂诱导小鼠外周感觉神经元中的 Kir3 电流 - 神经损伤的影响

Philip Stötzner, Viola Spahn, Melih Ö Celik, Dominika Labuz, Halina Machelska

Polyglycerol-opioid conjugate produces analgesia devoid of side effects

聚甘油-阿片类药物结合物可产生无副作用的镇痛作用

Sara González-Rodríguez, Mohiuddin A Quadir, Shilpi Gupta, Karolina A Walker, Xuejiao Zhang, Viola Spahn, Dominika Labuz, Antonio Rodriguez-Gaztelumendi, Martin Schmelz, Jan Joseph, Maria K Parr, Halina Machelska, Rainer Haag, Christoph Stein

Distinct roles of exogenous opioid agonists and endogenous opioid peptides in the peripheral control of neuropathy-triggered heat pain

外源性阿片类激动剂和内源性阿片肽在神经病变引发的热痛的外周控制中的不同作用

Dominika Labuz, Melih Ö Celik, Andreas Zimmer, Halina Machelska

The K(+) channel GIRK2 is both necessary and sufficient for peripheral opioid-mediated analgesia

K(+) 通道 GIRK2 是外周阿片类药物介导镇痛的必要和充分条件

Dinah Nockemann, Morgane Rouault, Dominika Labuz, Philip Hublitz, Kate McKnelly, Fernanda C Reis, Christoph Stein, Paul A Heppenstall

Immune cell-derived opioids protect against neuropathic pain in mice

免疫细胞衍生的阿片类药物可预防小鼠的神经性疼痛

Dominika Labuz, Yvonne Schmidt, Anja Schreiter, Heike L Rittner, Shaaban A Mousa, Halina Machelska