日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency

一种基于无启动子AAV6.2FF的肺部基因编辑平台,用于纠正肺表面活性蛋白B缺乏症。

Sylvia P Thomas ,Jakob M Domm ,Jacob P van Vloten ,Liqun Xu ,Arul Vadivel ,Jacob G E Yates ,Yanlong Pei ,Joelle Ingrao ,Laura P van Lieshout ,Sergio R Jackson ,Jessica A Minott ,Adithya Achuthan ,Yeganeh Mehrani ,Thomas M McAusland ,Wei Zhang ,Khalil Karimi ,Andrew E Vaughan ,Jondavid de Jong ,Martin H Kang ,Bernard Thebaud ,Sarah K Wootton

Ataxia telangiectasia mutated is required for efficient proximal airway epithelial cell regeneration following influenza A virus infection

共济失调毛细血管扩张症突变基因是甲型流感病毒感染后近端气道上皮细胞有效再生所必需的。

Warren, Rachel; Dylag, Andrew M; Behan, Molly; Domm, William; Yee, Min; Mayer-Pröschel, Margot; Martinez-Sobrido, Luis; O'Reilly, Michael A

A palpable chest wall mass in a 4-year-old boy

一名4岁男孩胸壁可触及肿块

Domm, Jakob M; Langley, Joanne M

A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency

一种靶向肺部的AAV载体可提高肺表面活性物质B缺乏症小鼠模型的存活率。

Martin H Kang ,Laura P van Lieshout # ,Liqun Xu # ,Jakob M Domm ,Arul Vadivel ,Laurent Renesme ,Christian Mühlfeld ,Maria Hurskainen ,Ivana Mižíková ,Yanlong Pei ,Jacob P van Vloten ,Sylvia P Thomas ,Claudia Milazzo ,Chanèle Cyr-Depauw ,Jeffrey A Whitsett ,Lawrence M Nogee ,Sarah K Wootton ,Bernard Thébaud

Optimized Pre-Clinical Grade Production of Two Novel Lentiviral Vector Pseudotypes for Lung Gene Delivery

用于肺基因传递的两种新型慢病毒载体假型的优化临床前级生产

María C Rosales Gerpe, Laura P van Lieshout, Jakob M Domm, Jacob P van Vloten, Jodre Datu, Joelle C Ingrao, Darrick L Yu, Jondavid de Jong, Theo J Moraes, Peter J Krell, Byram W Bridle, Sarah K Wootton

Interference chromatography: a novel approach to optimizing chromatographic selectivity and separation performance for virus purification

干扰色谱法:一种优化病毒纯化色谱选择性和分离性能的新方法

Santry, Lisa A; Jacquemart, Renaud; Vandersluis, Melissa; Zhao, Mochao; Domm, Jake M; McAusland, Thomas M; Shang, Xiaojiao; Major, Pierre M; Stout, James G; Wootton, Sarah K

The U3 and Env Proteins of Jaagsiekte Sheep Retrovirus and Enzootic Nasal Tumor Virus Both Contribute to Tissue Tropism

Jaagsiekte 绵羊逆转录病毒和地方性鼻肿瘤病毒的 U3 和 Env 蛋白均有助于组织向性

María C Rosales Gerpe, Laura P van Lieshout, Jakob M Domm, Joelle C Ingrao, Jodre Datu, Scott R Walsh, Darrick L Yu, Jondavid de Jong, Peter J Krell, Sarah K Wootton

A Novel Triple-Mutant AAV6 Capsid Induces Rapid and Potent Transgene Expression in the Muscle and Respiratory Tract of Mice

新型三突变体AAV6衣壳可在小鼠肌肉和呼吸道中诱导快速高效的转基因表达

van Lieshout, Laura P; Domm, Jakob M; Rindler, Tara N; Frost, Kathy L; Sorensen, Debra L; Medina, Sarah J; Booth, Stephanie A; Bridges, James P; Wootton, Sarah K

Neonatal hyperoxia depletes pulmonary vein cardiomyocytes in adult mice via mitochondrial oxidation

新生儿高氧血症通过线粒体氧化作用耗竭成年小鼠肺静脉心肌细胞。

Yee, Min; Cohen, Ethan David; Domm, William; Porter, George A Jr; McDavid, Andrew N; O'Reilly, Michael A

A concise revised Myeloma Comorbidity Index as a valid prognostic instrument in a large cohort of 801 multiple myeloma patients

一项纳入 801 例多发性骨髓瘤患者的大型队列研究表明,简明修订版骨髓瘤合并症指数可作为有效的预后工具。

Engelhardt, Monika; Domm, Anne-Saskia; Dold, Sandra Maria; Ihorst, Gabriele; Reinhardt, Heike; Zober, Alexander; Hieke, Stefanie; Baayen, Corine; Müller, Stefan Jürgen; Einsele, Hermann; Sonneveld, Pieter; Landgren, Ola; Schumacher, Martin; Wäsch, Ralph