日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Age-Dependent Effects of Voluntary Wheel Running Exercise on Voiding Behavior and Potential Age-Related Molecular Mechanisms in Mice

自愿轮跑运动对小鼠排尿行为的年龄依赖性影响及潜在的年龄相关分子机制

Teresa T Liu, Laura E Pascal, Scott R Bauer, Hannah N Miles, Jules B Panksepp, Granville L Lloyd, Lingjun Li, Donald B DeFranco, William A Ricke

Aging-Related Mitochondrial Dysfunction Is Associated With Fibrosis in Benign Prostatic Hyperplasia

衰老相关的线粒体功能障碍与良性前列腺增生的纤维化有关

Alexis E Adrian, Teresa T Liu, Laura E Pascal, Scott R Bauer, Donald B DeFranco, William A Ricke

Genomic glucocorticoid action in embryonic mouse neural stem cells

小鼠胚胎神经干细胞中的基因组糖皮质激素作用

Kimberly J Berry, Uma Chandran, Fangping Mu, Dinesh K Deochand, T Lei, Miriam Pagin, Silvia K Nicolis, A Paula Monaghan-Nichols, Inez Rogatsky, Donald B DeFranco

The SARS-CoV-2 E protein induces Toll-like receptor 2-mediated neonatal lung injury in a model of COVID-19 viremia that is rescued by the glucocorticoid ciclesonide

在 COVID-19 病毒血症模型中,SARS-CoV-2 E 蛋白可诱发 Toll 样受体 2 介导的新生儿肺损伤,而糖皮质激素环索奈德可挽救这一损伤

Heather L Menden, Sherry M Mabry, Aparna Venkatraman, Sheng Xia, Donald B DeFranco, Wei Yu, Venkatesh Sampath

E-cadherin deficiency promotes prostate macrophage inflammation and bladder overactivity in aged male mice

E-钙粘蛋白缺乏导致老年雄性小鼠前列腺巨噬细胞炎症和膀胱过度活动

Laura E Pascal, Taro Igarashi, Shinsuke Mizoguchi, Wei Chen, Lora H Rigatti, Caroline G Madigan, Rajiv Dhir, Wade Bushman, Donald B DeFranco, Naoki Yoshimura, Zhou Wang

Ciclesonide activates glucocorticoid signaling in neonatal rat lung but does not trigger adverse effects in the cortex and cerebellum

环索奈德可激活新生大鼠肺中的糖皮质激素信号,但不会在皮质和小脑中引发不良影响

Juliann D Jaumotte, Alexis L Franks, Erin M Bargerstock, Edwina Philip Kisanga, Heather L Menden, Alexis Ghersi, Mahmoud Omar, Liping Wang, Anthony Rudine, Kelly L Short, Neerupama Silswal, Timothy J Cole, Venkatesh Sampath, A Paula Monaghan-Nichols, Donald B DeFranco

Prostate-Specific Deletion of Cdh1 Induces Murine Prostatic Inflammation and Bladder Overactivity

前列腺特异性缺失 Cdh1 可诱发小鼠前列腺炎症和膀胱过度活动

Laura E Pascal, Shinsuke Mizoguchi, Wei Chen, Lora H Rigatti, Taro Igarashi, Rajiv Dhir, Pradeep Tyagi, Zeyu Wu, Zhenyu Yang, William C de Groat, Donald B DeFranco, Naoki Yoshimura, Zhou Wang

Tight junction protein claudin-1 is downregulated by TGF-β1 via MEK signaling in benign prostatic epithelial cells

在良性前列腺上皮细胞中,紧密连接蛋白claudin-1通过MEK信号通路被TGF-β1下调。

Ke Wang,Laura E Pascal,Feng Li,Wei Chen,Rajiv Dhir,Goundappa K Balasubramani,Donald B DeFranco,Naoki Yoshimura,Dalin He,Zhou Wang

Differential impact of paired patient-derived BPH and normal adjacent stromal cells on benign prostatic epithelial cell growth in 3D culture

患者来源的 BPH 和正常邻近基质细胞对 3D 培养中前列腺上皮细胞生长的不同影响

Wei Chen, Laura E Pascal, Ke Wang, Rajiv Dhir, Alexa M Sims, Robert Campbell, Gwenyth Gasper, Donald B DeFranco, Naoki Yoshimura, Zhou Wang

The role of prostaglandin and E series prostaglandin receptor type 4 receptors in the development of bladder overactivity in a rat model of chemically induced prostatic inflammation

前列腺素和 E 系列前列腺素受体 4 型受体在化学诱发前列腺炎症大鼠模型中膀胱过度活动发展中的作用

Shinsuke Mizoguchi, Amanda S Wolf-Johnson, Jianshu Ni, Kenichi Mori, Takahisa Suzuki, Eiichiro Takaoka, Hiromitsu Mimata, Donald B DeFranco, Zhou Wang, Lori A Birder, Naoki Yoshimura