日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Disruption of mitochondrial quality control genes promotes caspase-resistant cell survival following apoptotic stimuli

线粒体质量控制基因的破坏促进了凋亡刺激后胱天蛋白酶抗性的细胞存活

Yulia Kushnareva, Vivian Moraes, Julian Suess, Bjoern Peters, Donald D Newmeyer, Tomomi Kuwana

Targeting Ca2+ and Mitochondrial Homeostasis by Antipsychotic Thioridazine in Leukemia Cells

抗精神病药硫利达嗪靶向白血病细胞中的 Ca2+ 和线粒体稳态

Vivian W R Moraes, Vivian M Santos, Eloah R Suarez, Letícia S Ferraz, Rayssa de Mello Lopes, Giuliana P Mognol, Joana D Campeiro, João A Machado-Neto, Fabio D Nascimento, Mirian A F Hayashi, Ivarne L S Tersariol, Donald D Newmeyer, Tiago Rodrigues

Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilization

线粒体中凋亡诱导因子BAX的驻留比BAX寡聚化在促进膜通透性方面更为重要。

Tomomi Kuwana ,Louise E King ,Katia Cosentino ,Julian Suess ,Ana J Garcia-Saez ,Andrew P Gilmore ,Donald D Newmeyer

Phenotypic selection with an intrabody library reveals an anti-apoptotic function of PKM2 requiring Mitofusin-1

利用胞内抗体库进行表型选择,发现 PKM2 具有抗凋亡功能,需要 Mitofusin-1

Tong Liu, Tomomi Kuwana, Hongkai Zhang, Matthew G Vander Heiden, Richard A Lerner, Donald D Newmeyer

Pro-apoptotic Bax molecules densely populate the edges of membrane pores

促凋亡的 Bax 分子密集地分布在膜孔的边缘

Tomomi Kuwana, Norman H Olson, William B Kiosses, Bjoern Peters, Donald D Newmeyer

Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization

Opa1介导的嵴开放依赖于Bax/Bak和BH3,是细胞凋亡所必需的,并且不依赖于Bak寡聚化

Ryuji Yamaguchi, Lydia Lartigue, Guy Perkins, Ray T Scott, Amruta Dixit, Yulia Kushnareva, Tomomi Kuwana, Mark H Ellisman, Donald D Newmeyer