日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel Pfk13 and Pfubp1 genotypes in African Plasmodium falciparum isolates exhibiting reduced susceptibility to the antimalarials artemisinin and lumefantrine

非洲恶性疟原虫分离株中发现的新型 Pfk13 和 Pfubp1 基因型对青蒿素和蒿甲醚这两种抗疟药的敏感性降低。

Pratt, Sade; van Schalkwyk, Donelly A; Stewart, Lindsay; Hocke, Emma Filtenborg; Mannan, Samirah; Berry, Charlotte; Muwanguzi-Karugaba, Julian; Nolder, Debbie; Rogers, Claire; Chiodini, Peter L; Henrici, Ryan C; Moss, Sophie; Billows, Nina; Phelan, Jody; Clark, Taane G; Campino, Susana; Sutherland, Colin J

Flavin-deficient erythrocytes offer protection against malaria parasites

缺乏黄素的红细胞能够抵抗疟原虫的感染。

Hemasa, Ayman; van Loon, Welmoed; Fu, Jonathan; Spry, Christina; Jäger, Julia; van Schalkwyk, Donelly A; Reverberi, Roberto; Ndoli, Jules; Mockenhaupt, Frank P; Contini, Carlo; Saliba, Kevin J

Genome sequencing of Plasmodium malariae identifies continental segregation and mutations associated with reduced pyrimethamine susceptibility

疟原虫基因组测序确定了大陆隔离和与乙胺嘧啶敏感性降低相关的突变

Amy Ibrahim, Franziska Mohring, Emilia Manko, Donelly A van Schalkwyk, Jody E Phelan, Debbie Nolder, Steffen Borrmann, Ayola A Adegnika, Silvia Maria Di Santi, Mohammad Shafiul Alam, Dinesh Mondal, Francois Nosten, Colin J Sutherland, Robert W Moon, Taane G Clark, Susana Campino0

Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission.

疟原虫环核苷酸磷酸二酯酶抑制剂可阻断无性血液期发育和蚊子传播

Gomez-Gonzalez Paula-Josefina, Gupta Antima, Drought Laura G, Patel Avnish, Okombo John, van der Watt Mariëtte, Walker-Gray Ryan, Schindler Kyra A, Burkhard Anna Y, Yeo Tomas, Narwal Sunil K, Bloxham Talia S, Flueck Christian, Walker Eloise M, Rey Joshua A, Fairhurst Kate J, Reader Janette, Park Heekuk, Pollard Harry G, Stewart Lindsay B, Brandner-Garrod Luke, Kristan Mojca, Sterk Geert-Jan, van Nuland Youri M, Manko Emilia, van Schalkwyk Donelly A, Zheng Yang, Leurs Rob, Dechering Koen J, Aguiar Anna Caroline C, Guido Rafael V C, Pereira Dhelio B, Tumwebaze Patrick K, Nosbya Samuel L, Rosenthal Philip J, Cooper Roland A, Palmer Mike, Parkinson Tanya, Burrows Jeremy N, Uhlemann Anne-Catrin, Birkholtz Lyn-Marié, Small-Saunders Jennifer L, Duffy James, Fidock David A, Brown Alan, Gardner Mark, Baker David A

Treatment Failure in a UK Malaria Patient Harboring Genetically Variant Plasmodium falciparum From Uganda With Reduced In Vitro Susceptibility to Artemisinin and Lumefantrine

英国一名携带遗传变异恶性疟原虫的乌干达疟疾患者治疗失败,其体外对青蒿素和卢美凡特林的敏感性降低

Donelly A van Schalkwyk, Sade Pratt, Debbie Nolder, Lindsay B Stewart, Helen Liddy, Julian Muwanguzi-Karugaba, Khalid B Beshir, Dawn Britten, Emma Victory, Claire Rogers, James Millard, Michael Brown, Laura E Nabarro, Andrew Taylor, Bernadette C Young, Peter L Chiodini, Colin J Sutherland

Cation ATPase (ATP4) Orthologue Replacement in the Malaria Parasite Plasmodium knowlesi Reveals Species-Specific Responses to ATP4-Targeting Drugs

疟原虫诺氏疟原虫中的阳离子 ATPase (ATP4) 直系同源物替换揭示了对 ATP4 靶向药物的物种特异性反应

Franziska Mohring #, Donelly A van Schalkwyk #, Ryan C Henrici, Benjamin Blasco, Didier Leroy, Colin J Sutherland, Robert W Moon

Diagnostic accuracy and limit of detection of ten malaria parasite lactate dehydrogenase-based rapid tests for Plasmodium knowlesi and P. falciparum

十种基于乳酸脱氢酶的疟原虫快速检测方法对诺氏疟原虫和恶性疟原虫的诊断准确性和检测限

Tan, Angelica F; Sakam, Sitti Saimah Binti; Rajahram, Giri S; William, Timothy; Abd Rachman Isnadi, Mohammad Faruq; Daim, Sylvia; Barber, Bridget E; Kho, Steven; Sutherland, Colin J; Anstey, Nicholas M; Yerlikaya, Seda; van Schalkwyk, Donelly A; Grigg, Matthew J

Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer

半合成 Cryptolepine 类似物可作为治疗疟疾、非洲人类锥虫病和癌症的可持续药物的潜在来源

Yabalu Z Abacha, Arnold Donkor Forkuo, Stephen Y Gbedema, Nimisha Mittal, Sabine Ottilie, Frances Rocamora, Elizabeth A Winzeler, Donelly A van Schalkwyk, John M Kelly, Martin C Taylor, Janette Reader, Lyn-Marie Birkholtz, David R Lisgarten, Jeremy K Cockcroft, John N Lisgarten, Rex A Palmer, Rosema

Corrigendum to 'A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infections'

对“一种用于检测多克隆感染中组氨酸富集蛋白 2 和 3 (pfhrp2 和 pfhrp3) 缺失的恶性疟原虫的新型多重 qPCR 检测”的更正

Grignard, Lynn; Nolder, Debbie; Sepulveda, Nuno; Berhane, Araia; Mihreteab, Selam; Kaaya, Robert; Phelan, Jody; Moser, Kara; van Schalkwyk, Donelly A; Campino, Susana; Parr, Jonathan B; Juliano, Jonathan J; Chiodini, Peter; Cunningham, Jane; Sutherland, Colin J; Drakeley, Chris; Beshir, Khalid B

Ex vivo susceptibility to new antimalarial agents differs among human-infecting Plasmodium species

人类感染疟原虫的种类对新型抗疟药物的体外敏感性存在差异

Donelly A van Schalkwyk, Robert W Moon, Maëlle Duffey, Didier Leroy, Colin J Sutherland