日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Subacute exposure of male adolescent rats to 2,2',5,5'-tetrachlorobiphenyl-4-ol via a polymeric implant causes gene expression changes in the brain and metabolomic disruption in serum.

雄性青春期大鼠通过聚合物植入物亚急性暴露于 2,2',5,5'-四氯联苯-4-醇,会导致大脑基因表达变化和血清代谢组紊乱

Wang Hui, Bullert Amanda J, Linahon Morgan J, Dailey Michael E, Doorn Jonathan A, Klingelhutz Aloysius J, Ankrum James A, Lehmler Hans-Joachim

Selective dopaminergic neurotoxicity modulated by inherent cell-type specific neurobiology

细胞类型特异性神经生物学调控的选择性多巴胺能神经毒性

Currim, Fatema; Tanwar, Reeya; Brown-Leung, Josephine M; Paranjape, Neha; Liu, Jennifer; Sanders, Laurie H; Doorn, Jonathan A; Cannon, Jason R

Enhanced Catecholamine Flux and Impaired Carbonyl Metabolism Disrupt Cardiac Mitochondrial Oxidative Phosphorylation in Diabetes Patients

儿茶酚胺通量增强和羰基代谢受损会破坏糖尿病患者的心脏线粒体氧化磷酸化

Nelson, Margaret-Ann M; Efird, Jimmy T; Kew, Kimberly A; Katunga, Lalage A; Monroe, T Blake; Doorn, Jonathan A; Beatty, Cherese N; Shi, Qian; Akhter, Shahab A; Alwair, Hazaim; Robidoux, Jacques; Anderson, Ethan J

In vitro inhibition of glutathione-S-transferase by dopamine and its metabolites, 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylacetic acid

多巴胺及其代谢产物3,4-二羟基苯乙醛和3,4-二羟基苯乙酸对谷胱甘肽-S-转移酶的体外抑制作用

Crawford, Rachel A; Bowman, Kate R; Cagle, Brianna S; Doorn, Jonathan A

The Effects of Polychlorinated Biphenyl Exposure During Adolescence on the Nervous System: A Comprehensive Review

青少年时期多氯联苯暴露对神经系统的影响:一项综合综述

Bullert, Amanda J; Doorn, Jonathan A; Stevens, Hanna E; Lehmler, Hans-Joachim

Fragment-Based Nuclear Magnetic Resonance Screen against a Regulator of G Protein Signaling Identifies a Binding "Hot Spot"

基于片段的核磁共振筛选针对G蛋白信号传导调节因子,鉴定出一个结合“热点”

Hayes, Michael P; O'Brien, Joseph B; Crawford, Rachel A; Fowler, C Andrew; Yu, Liping; Doorn, Jonathan A; Roman, David L

Atropselective Oxidation of 2,2',3,3',4,6'-Hexachlorobiphenyl (PCB 132) to Hydroxylated Metabolites by Human Liver Microsomes and Its Implications for PCB 132 Neurotoxicity

人肝微粒体对2,2',3,3',4,6'-六氯联苯(PCB 132)的对映选择性氧化及其对PCB 132神经毒性的影响

Uwimana, Eric; Cagle, Brianna; Yeung, Coby; Li, Xueshu; Patterson, Eric V; Doorn, Jonathan A; Lehmler, Hans-Joachim

Biochemical characterization of the catecholaldehyde reactivity of L-carnosine and its therapeutic potential in human myocardium

L-肌肽儿茶酚醛反应性的生化特性及其在人类心肌中的治疗潜力

Nelson, Margaret-Ann M; Builta, Zachariah J; Monroe, T Blake; Doorn, Jonathan A; Anderson, Ethan J

Screen Targeting Lung and Prostate Cancer Oncogene Identifies Novel Inhibitors of RGS17 and Problematic Chemical Substructures

针对肺癌和前列腺癌癌基因的筛选鉴定出RGS17的新型抑制剂及其有问题的化学亚结构

Bodle, Christopher R; Schamp, Josephine H; O'Brien, Joseph B; Hayes, Michael P; Wu, Meng; Doorn, Jonathan A; Roman, David L

Antioxidant-Mediated Modulation of Protein Reactivity for 3,4-Dihydroxyphenylacetaldehyde, a Toxic Dopamine Metabolite

抗氧化剂介导的蛋白质对3,4-二羟基苯乙醛(一种有毒的多巴胺代谢物)反应性的调节

Anderson, David G; Florang, Virginia R; Schamp, Josephine H; Buettner, Garry R; Doorn, Jonathan A