日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Molecular insights into the regulation of GNPTαβ by LYSET

LYSET调控GNPTαβ的分子机制研究

Yang, Xi; Doray, Balraj; Henn, Danielle; Venkatarangan, Varsha; Jennings, Benjamin C; Dong, Zhongzheng; Liang, Jiaxuan; Zhang, Weichao; Zhang, Bokai; Yu, Linchen; Chen, Liang; Kornfeld, Stuart; Li, Ming

Subtle cellular phenotypes inform pathological and benign genetic mutants in the Iduronate-2 sulfatase gene

细微的细胞表型可提示艾杜糖醛酸-2硫酸酯酶基因的致病性和良性遗传突变体。

Viswanathan, Anushka; Elia, Serena; Le, Steven Q; Hurt, Sarah; Doray, Balraj; Waligorski, Jason; Kelley, Kylan; Buchser, William; Dickson, Patricia

Reduced heparan sulfate levels in cerebrospinal fluid reflect brain neuron correction in Sanfilippo B mice

Sanfilippo B 小鼠脑脊液中硫酸乙酰肝素水平降低反映了脑神经元的修复。

Le, Steven Q; Sorensen, Alexander; Sukupolvi, Soila; Jewhurst, Gianna; Austin, Grant; Doray, Balraj; Cooper, Jonathan D; Dickson, Patricia I

GABAergic interneurons contribute to the fatal seizure phenotype of CLN2 disease mice

GABA能中间神经元与CLN2疾病小鼠的致命性癫痫表型有关。

Takahashi, Keigo; Rensing, Nicholas R; Eultgen, Elizabeth M; Williams, Letitia L; Wang, Sophie H; Nelvagal, Hemanth R; Le, Steven Q; Roberts, Marie S; Doray, Balraj; Han, Edward B; Dickson, Patricia I; Wong, Michael; Sands, Mark S; Cooper, Jonathan D

An unconventional HxD motif orchestrates coatomer-dependent coronavirus morphogenesis

一种非常规的HxD基序调控着依赖于衣壳蛋白的冠状病毒形态发生。

Mohona, Surovi; Shakya, Anil K; Singh, Suruchi; Kearns, Fiona L; Jemison, Kezia; Erramilli, Satchal; Dey, Debajit; Qing, Enya; Jennings, Benjamin C; Doray, Balraj; Kossiakoff, Anthony A; Amaro, Rommie E; Klose, Thomas; Gallagher, Tom; Hasan, S Saif

Disease-causing missense mutations within the N-terminal transmembrane domain of GlcNAc-1-phosphotransferase impair endoplasmic reticulum translocation or Golgi retention

GlcNAc-1-磷酸转移酶N端跨膜结构域内的致病性错义突变会损害内质网转运或高尔基体滞留。

Lee, Wang-Sik; Jennings, Benjamin C; Doray, Balraj; Kornfeld, Stuart

Recycling of Golgi glycosyltransferases requires direct binding to coatomer

高尔基糖基转移酶的回收利用需要与衣壳蛋白直接结合。

Liu, Lin; Doray, Balraj; Kornfeld, Stuart

Engineering of GlcNAc-1-Phosphotransferase for Production of Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy

利用工程改造 GlcNAc-1-磷酸转移酶生产高磷酸化溶酶体酶,用于酶替代疗法

Liu, Lin; Lee, Wang-Sik; Doray, Balraj; Kornfeld, Stuart

Role of spacer-1 in the maturation and function of GlcNAc-1-phosphotransferase

间隔区1在GlcNAc-1-磷酸转移酶的成熟和功能中的作用

Liu, Lin; Lee, Wang-Sik; Doray, Balraj; Kornfeld, Stuart

Multiple Domains of GlcNAc-1-phosphotransferase Mediate Recognition of Lysosomal Enzymes

GlcNAc-1-磷酸转移酶的多个结构域介导对溶酶体酶的识别

van Meel, Eline; Lee, Wang-Sik; Liu, Lin; Qian, Yi; Doray, Balraj; Kornfeld, Stuart