Caspase-2 deficiency drives pathogenic liver polyploidy and increases age-associated hepatocellular carcinoma in mice.
Caspase-2 缺乏会导致小鼠肝脏发生致病性多倍体，并增加与年龄相关的肝细胞癌。
期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.aeb2571
Dorstyn Loretta, Lim Yoon, Scanlan Jack, McLennan Emma, De Bellis Dylan, Katschner Michael, Finnie John, Emery-Corbin Samantha, Yousef Jumana, Dagley Laura F, Kok Chung H, Shah Sonia S, Takahashi Chiaki, Febbraio Mark A, Kumar Sharad
