High-Content Small Molecule Screen Identifies a Novel Compound That Restores AP-4-Dependent Protein Trafficking in Neuronal Models of AP-4-Associated Hereditary Spastic Paraplegia
高内涵小分子筛选鉴定出一种新型化合物,可在 AP-4 相关遗传性痉挛性截瘫的神经元模型中恢复 AP-4 依赖性蛋白质运输
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doi:10.21203/rs.3.rs-3036166/v1
Afshin Saffari, Barbara Brechmann, Cedric Boeger, Wardiya Afshar Saber, Hellen Jumo, Dosh Whye, Delaney Wood, Lara Wahlster, Julian Alecu, Marvin Ziegler, Marlene Scheffold, Kellen Winden, Jed Hubbs, Elizabeth Buttermore, Lee Barrett, Georg Borner, Alexandra Davies, Mustafa Sahin, Darius Ebrahimi-Fa