Dougherty Dennis A相关文献与解析，生知库

Continuous Nicotine Monitors for Personal Nicotine Pharmacokinetics: A Receptor-Aware Research Agenda

用于个人尼古丁药代动力学研究的连续尼古丁监测器：一种基于受体机制的研究议程

Nichols, Aaron L; Marotta, Christopher B; Lukas, Heather; Friesenhahn, Nicholas J; Wagenaar, Daniel A; Mayo, Stephen L; Dougherty, Dennis A; Benowitz, Neal L; Gao, Wei; Muthusamy, Anand K; Lester, Henry A

信号转导

发表日期：2025

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Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids

交互式计算和实验方法提高了基于周质结合蛋白的尼古丁生物传感器在生物体液测量中的灵敏度。

期刊:Protein Engineering Design & Selection

影响因子:3.4

doi:10.1093/protein/gzae003

Haloi, Nandan; Huang, Shan; Nichols, Aaron L; Fine, Eve J; Friesenhahn, Nicholas J; Marotta, Christopher B; Dougherty, Dennis A; Lindahl, Erik; Howard, Rebecca J; Mayo, Stephen L; Lester, Henry A

发表日期：2024

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Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane

细胞内选择性血清素再摄取抑制剂：细胞质、内质网和细胞膜的时间分辨率

期刊:Journal of Neuroscience

影响因子:4

doi:10.1523/JNEUROSCI.1519-22.2022

Nichols, Aaron L; Blumenfeld, Zack; Luebbert, Laura; Knox, Hailey J; Muthusamy, Anand K; Marvin, Jonathan S; Kim, Charlene H; Grant, Stephen N; Walton, David P; Cohen, Bruce N; Hammar, Rebekkah; Looger, Loren; Artursson, Per; Dougherty, Dennis A; Lester, Henry A

细胞生物学

发表日期：2023

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Three Mutations Convert the Selectivity of a Protein Sensor from Nicotinic Agonists to S-Methadone for Use in Cells, Organelles, and Biofluids

三种突变将蛋白质传感器的选择性从尼古丁激动剂转变为S-美沙酮，可用于细胞、细胞器和生物体液中。

期刊:Journal of the American Chemical Society

影响因子:15.6

doi:10.1021/jacs.2c02323

Muthusamy, Anand K; Kim, Charlene H; Virgil, Scott C; Knox, Hailey J; Marvin, Jonathan S; Nichols, Aaron L; Cohen, Bruce N; Dougherty, Dennis A; Looger, Loren L; Lester, Henry A

细胞生物学

发表日期：2022

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Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands

更正：新型戒烟配体传感器的荧光激活机制及药物渗透成像

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.85479

Nichols, Aaron L; Blumenfeld, Zack; Fan, Chengcheng; Luebbert, Laura; Blom, Annet E M; Cohen, Bruce N; Marvin, Jonathan S; Borden, Philip M; Kim, Charlene H; Muthusamy, Anand K; Shivange, Amol V; Knox, Hailey J; Campello, Hugo Rego; Wang, Jonathan H; Dougherty, Dennis A; Looger, Loren L; Gallagher, Timothy; Rees, Douglas C; Lester, Henry A

发表日期：2022

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5-HT(3) Receptor MX Helix Contributes to Receptor Function

5-HT(3)受体MX螺旋结构有助于受体功能

期刊:ACS Chemical Neuroscience

影响因子:3.9

doi:10.1021/acschemneuro.2c00339

Mocatta, James; Mesoy, Susanne M; Dougherty, Dennis A; Lummis, Sarah C R

Synthesis and Biological Evaluation of Pyrroloindolines as Positive Allosteric Modulators of the α1β2γ2 GABA(A) Receptor

吡咯并吲哚啉类化合物作为α1β2γ2 GABA(A)受体正向变构调节剂的合成及生物学评价

期刊:ACS Medicinal Chemistry Letters

影响因子:4

doi:10.1021/acsmedchemlett.0c00340

Blom, Annet E M; Su, Justin Y; Repka, Lindsay M; Reisman, Sarah E; Dougherty, Dennis A

信号转导

发表日期：2020

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A triad of residues is functionally transferrable between 5-HT(3) serotonin receptors and nicotinic acetylcholine receptors

5-HT(3)血清素受体和尼古丁乙酰胆碱受体之间可功能性地转移一组残基。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M117.810432

Mosesso, Richard; Dougherty, Dennis A

Secondary Ammonium Agonists Make Dual Cation-π Interactions in α4β2 Nicotinic Receptors

二级铵激动剂在α4β2尼古丁受体中产生双重阳离子-π相互作用

期刊:eNeuro

影响因子:2.7

doi:10.1523/ENEURO.0032-17.2017

Post, Michael R; Tender, Gabrielle S; Lester, Henry A; Dougherty, Dennis A

信号转导

发表日期：2017

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The Cation-π Interaction in Chemistry and Biology

化学和生物学中的阳离子-π相互作用

Continuous Nicotine Monitors for Personal Nicotine Pharmacokinetics: A Receptor-Aware Research Agenda

用于个人尼古丁药代动力学研究的连续尼古丁监测器：一种基于受体机制的研究议程

Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids

交互式计算和实验方法提高了基于周质结合蛋白的尼古丁生物传感器在生物体液测量中的灵敏度。

Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane

细胞内选择性血清素再摄取抑制剂：细胞质、内质网和细胞膜的时间分辨率

Three Mutations Convert the Selectivity of a Protein Sensor from Nicotinic Agonists to S-Methadone for Use in Cells, Organelles, and Biofluids

三种突变将蛋白质传感器的选择性从尼古丁激动剂转变为S-美沙酮，可用于细胞、细胞器和生物体液中。

Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands

更正：新型戒烟配体传感器的荧光激活机制及药物渗透成像

5-HT(3) Receptor MX Helix Contributes to Receptor Function

5-HT(3)受体MX螺旋结构有助于受体功能

Synthesis and Biological Evaluation of Pyrroloindolines as Positive Allosteric Modulators of the α1β2γ2 GABA(A) Receptor

吡咯并吲哚啉类化合物作为α1β2γ2 GABA(A)受体正向变构调节剂的合成及生物学评价

A triad of residues is functionally transferrable between 5-HT(3) serotonin receptors and nicotinic acetylcholine receptors

5-HT(3)血清素受体和尼古丁乙酰胆碱受体之间可功能性地转移一组残基。

Secondary Ammonium Agonists Make Dual Cation-π Interactions in α4β2 Nicotinic Receptors

二级铵激动剂在α4β2尼古丁受体中产生双重阳离子-π相互作用