日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

5-Hydroxymethylated Biomarkers in Cell-Free DNA Predict Occult Colorectal Cancer up to 36 Months Before Diagnosis in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

在前列腺癌、肺癌、结直肠癌和卵巢癌筛查试验中,游离DNA中的5-羟甲基化生物标志物可预测隐匿性结直肠癌,预测时间最长可达诊断前36个月。

West-Szymanski, Diana C; Zhang, Zhou; Cui, Xiao-Long; Kowitwanich, Krissana; Gao, Lu; Deng, Zifeng; Dougherty, Urszula; Williams, Craig; Merkle, Shannon; He, Chuan; Zhang, Wei; Bissonnette, Marc

Epigenetic DNA Modifications Upregulate SPRY2 in Human Colorectal Cancers.

表观遗传DNA修饰上调人类结直肠癌中的SPRY2

Stuckel Alexei J, Zeng Shuai, Lyu Zhen, Zhang Wei, Zhang Xu, Dougherty Urszula, Mustafi Reba, Zhang Qiong, Joshi Trupti, Bissonnette Marc, Choudhury Samrat Roy, Khare Sharad

A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation

5-羟甲基胞嘧啶的人体组织图谱通过基因和增强子调控展现出组织特异性。

Cui, Xiao-Long; Nie, Ji; Ku, Jeremy; Dougherty, Urszula; West-Szymanski, Diana C; Collin, Francois; Ellison, Christopher K; Sieh, Laura; Ning, Yuhong; Deng, Zifeng; Zhao, Carolyn W T; Bergamaschi, Anna; Pekow, Joel; Wei, Jiangbo; Beadell, Alana V; Zhang, Zhou; Sharma, Geeta; Talwar, Raman; Arensdorf, Patrick; Karpus, Jason; Goel, Ajay; Bissonnette, Marc; Zhang, Wei; Levy, Samuel; He, Chuan

A novel mouse model of sporadic colon cancer induced by combination of conditional Apc genes and chemical carcinogen in the absence of Cre recombinase

一种新型小鼠散发性结肠癌模型,该模型由条件性 Apc 基因和化学致癌物联合诱导,且不涉及 Cre 重组酶。

Souris, Jeffrey S; Zhang, Hannah J; Dougherty, Urszula; Chen, Nai-Tzu; Waller, Joseph V; Lo, Leu-Wei; Hart, John; Chen, Chin-Tu; Bissonnette, Marc

Increased mucosal expression of miR-215 precedes the development of neoplasia in patients with long-standing ulcerative colitis

在长期溃疡性结肠炎患者中,黏膜中 miR-215 表达增加先于肿瘤的发生。

Pekow, Joel; Meckel, Katherine; Dougherty, Urszula; Haider, Haider I; Deng, Zifeng; Hart, John; Rubin, David T; Bissonnette, Marc

IV Administered Gadodiamide Enters the Lumen of the Prostatic Glands: X-Ray Fluorescence Microscopy Examination of a Mouse Model

静脉注射钆双胺进入前列腺管腔:小鼠模型X射线荧光显微镜检查

Mustafi, Devkumar; Gleber, Sophie-Charlotte; Ward, Jesse; Dougherty, Urszula; Zamora, Marta; Markiewicz, Erica; Binder, David C; Antic, Tatjana; Vogt, Stefan; Karczmar, Gregory S; Oto, Aytekin

X-ray fluorescence microscopy demonstrates preferential accumulation of a vanadium-based magnetic resonance imaging contrast agent in murine colonic tumors

X射线荧光显微镜显示,钒基磁共振成像造影剂优先积聚在小鼠结肠肿瘤中。

Mustafi, Devkumar; Ward, Jesse; Dougherty, Urszula; Bissonnette, Marc; Hart, John; Vogt, Stefan; Karczmar, Gregory S

The renin-angiotensin system mediates EGF receptor-vitamin d receptor cross-talk in colitis-associated colon cancer

肾素-血管紧张素系统介导结肠炎相关结肠癌中的EGF受体-维生素D受体相互作用

Dougherty, Urszula; Mustafi, Reba; Sadiq, Farhana; Almoghrabi, Anas; Mustafi, Devkumar; Kreisheh, Maggi; Sundaramurthy, Sumana; Liu, Weicheng; Konda, Vani J; Pekow, Joel; Khare, Sharad; Hart, John; Joseph, Loren; Wyrwicz, Alice; Karczmar, Gregory S; Li, Yan Chun; Bissonnette, Marc

Intestinal epithelial vitamin D receptor signaling inhibits experimental colitis

肠道上皮维生素D受体信号传导抑制实验性结肠炎

Liu, Weicheng; Chen, Yunzi; Golan, Maya Aharoni; Annunziata, Maria L; Du, Jie; Dougherty, Urszula; Kong, Juan; Musch, Mark; Huang, Yong; Pekow, Joel; Zheng, Changqing; Bissonnette, Marc; Hanauer, Stephen B; Li, Yan Chun

Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis

在小鼠偶氮甲烷结肠癌模型中,表皮生长因子受体信号传导是微腺瘤形成所必需的。

Fichera, Alessandro; Little, Nathaniel; Jagadeeswaran, Sujatha; Dougherty, Urszula; Sehdev, Amikar; Mustafi, Reba; Cerda, Sonia; Yuan, Weihua; Khare, Sharad; Tretiakova, Maria; Gong, Can; Tallerico, Michael; Cohen, Greg; Joseph, Loren; Hart, John; Turner, Jerrold R; Bissonnette, Marc