日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A cellular model of TDP-43 induces phosphorylated TDP-43 aggregation with distinct changes in solubility and autophagy dysregulation.

TDP-43 的细胞模型可诱导磷酸化 TDP-43 聚集,并引起溶解度和自噬失调的明显变化

Dopler Matthew B, Abeer Muhammad I, Arezoumandan Sanaz, Cox Keyshawn, Petersen Tyler L, Daniel Esther H, Cannon Carlton L 3rd, Bautista Angelica, Blancher Kennedy D, Bland Alysia M, Bond Kylie J, Davis Dominque A, Francois Jessica M, McCray Eliana J, Morgan Justin M, Pulliam Jessica L, Robinson Zymir A, Taylor Mykia J, Dowell James A, Cairns Nigel J, Gitcho Michael A

Safety and Pharmacokinetics of Taniborbactam (VNRX-5133) with Cefepime in Subjects with Various Degrees of Renal Impairment

坦尼博巴坦(VNRX-5133)联合头孢吡肟治疗不同程度肾功能损害患者的安全性和药代动力学

Dowell, James A; Marbury, Thomas C; Smith, William B; Henkel, Tim

Safety and Pharmacokinetics in Human Volunteers of Taniborbactam (VNRX-5133), a Novel Intravenous β-Lactamase Inhibitor

新型静脉注射β-内酰胺酶抑制剂Taniborbactam (VNRX-5133)在人体志愿者中的安全性和药代动力学

Dowell, James A; Dickerson, Daniel; Henkel, Tim

TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics

TDP-43 与线粒体蛋白相互作用,这些蛋白对线粒体自噬和线粒体动力学至关重要。

Davis, Stephani A; Itaman, Sheed; Khalid-Janney, Christopher M; Sherard, Justin A; Dowell, James A; Cairns, Nigel J; Gitcho, Michael A

Iron Deprivation Induces Transcriptional Regulation of Mitochondrial Biogenesis

铁缺乏诱导线粒体生物合成的转录调控

Rensvold, Jarred W; Krautkramer, Kimberly A; Dowell, James A; Denu, John M; Pagliarini, David J

Mechanisms of Nrf2 protection in astrocytes as identified by quantitative proteomics and siRNA screening

通过定量蛋白质组学和siRNA筛选鉴定星形胶质细胞中Nrf2保护机制

Dowell, James A; Johnson, Jeffrey A

Rat brain neuropeptidomics: tissue collection, protease inhibition, neuropeptide extraction, and mass spectrometric analysis

大鼠脑神经肽组学:组织采集、蛋白酶抑制、神经肽提取和质谱分析

Sturm, Robert M; Dowell, James A; Li, Lingjun

Identification of astrocyte secreted proteins with a combination of shotgun proteomics and bioinformatics

结合鸟枪法蛋白质组学和生物信息学鉴定星形胶质细胞分泌蛋白

Dowell, James A; Johnson, Jeffrey A; Li, Lingjun

Comparison of two-dimensional fractionation techniques for shotgun proteomics

二维分级分离技术在鸟枪法蛋白质组学中的比较

Dowell, James A; Frost, Dustin C; Zhang, Jiang; Li, Lingjun