日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Uncovering genetic interactions in the DNA repair network in response to endogenous damage and ionizing radiation.

揭示DNA修复网络中基因相互作用对内源性损伤和电离辐射的反应。

Nebenfuehr Benjamin, Sanford Lynn, Taylor Erin R, Ball Kerri, Woods-Killam Catherine E, Ghasemi Hannah I, Proctor Bruce 3rd, Ortega Raquel, Sempeck Colin, Dowell Robin D, Arnoult Nausica

Enhancer RNA transcription pinpoints functional genetic variants linked to asthma.

增强子RNA转录可精确定位与哮喘相关的功能性基因变异

Sasse Sarah K, Dahlin Amber, Sanford Lynn, Gruca Margaret A, Gupta Arnav, Gally Fabienne, Wu Ann Chen, Iribarren Carlos, Dowell Robin D, Weiss Scott T, Gerber Anthony N

LIET model: capturing the kinetics of RNA polymerase from loading to termination

LIET模型:捕捉RNA聚合酶从装载到终止的动力学过程

Stanley, Jacob T; Barone, Georgia E F; Townsend, Hope A; Sigauke, Rutendo F; Allen, Mary A; Dowell, Robin D

TF Profiler: a transcription factor inference method that broadly measures transcription factor activity and identifies mechanistically distinct networks

TF Profiler:一种转录因子推断方法,可广泛测量转录因子活性并识别机制不同的网络。

Jones, Taylor; Sigauke, Rutendo F; Sanford, Lynn; Taatjes, Dylan J; Allen, Mary A; Dowell, Robin D

Multi-omics and biochemical reconstitution reveal CDK7-dependent mechanisms controlling RNA polymerase II function at gene 5'- and 3' ends.

多组学和生化重建揭示了 CDK7 依赖性机制控制 RNA 聚合酶 II 在基因 5' 端和 3' 端的功能

Luyties Olivia, Sanford Lynn, Rodino Jessica, Nagel Michael, Jones Taylor, Rimel Jenna K, Ebmeier Christopher C, Palacio Megan, Shelby Grace S, Cozzolino Kira, Brennan Finn, Hartzog Axel, Saucedo Mirzam B, Watts Lotte P, Spencer Sabrina, Kugel Jennifer F, Dowell Robin D, Taatjes Dylan J

Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome

介导激酶抑制可抑制唐氏综合征中过度活跃的干扰素信号传导

Cozzolino, Kira A; Sanford, Lynn; Hunter, Samuel; Molison, Kayla; Erickson, Benjamin; Courvan, Meaghan C S; Jones, Taylor; Ajit, Deepa; Galbraith, Matthew D; Espinosa, Joaquín M; Bentley, David; Allen, Mary Ann; Dowell, Robin D; Taatjes, Dylan J

Functional Variant Discovery Identifies a Novel Genetic Link Between SPRY2, Wood Smoke, and Asthma

功能性变异发现揭示了SPRY2、木烟和哮喘之间的一种新的遗传联系

Gupta, Arnav; Dahlin, Amber; Macario, Alejandra; Gally, Fabienne; Weaver, Michael R; Guarino, Samuel; Kahn, Louisa; Sanford, Lynn; Gruca, Margaret A; Cho, Michael H; Dowell, Robin D; Weiss, Scott T; Sasse, Sarah K; Gerber, Anthony N

DYRK1A in blood and immune function: implications in leukemia, inflammatory disorders, infection and Down syndrome

DYRK1A 在血液和免疫功能中的作用:与白血病、炎症性疾病、感染和唐氏综合征的关系

Rozen, Esteban J; Dowell, Robin D; Allen, Mary A

Atlas of nascent RNA transcripts reveals tissue-specific enhancer to gene linkages

新生RNA转录本图谱揭示组织特异性增强子与基因的联系

Sigauke, Rutendo F; Sanford, Lynn; Maas, Zachary L; Jones, Taylor; Stanley, Jacob T; Townsend, Hope A; Allen, Mary A; Dowell, Robin D

Histone Deacetylase Inhibitor Largazole Deactivates A Subset of Superenchancers and Causes Mitotic Chromosome Mis-alignment by Suppressing SP1 and BRD4

组蛋白去乙酰化酶抑制剂拉格唑通过抑制SP1和BRD4,使一部分超增强子失活并导致有丝分裂染色体错位。

Sanchez, Gilson J; Liu, Zeyu; Hunter, Samuel; Xu, Quanbin; Westfall, Jessica T V; Wheeler, Graycen E; Toomey, Cathryn; Taatjes, Dylan; Allen, Mary; Dowell, Robin D; Liu, Xuedong