日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Outbreak of Invasive Serratia marcescens among Persons Incarcerated in a State Prison, California, USA, March 2020-December 2022

2020年3月至2022年12月，美国加利福尼亚州一所州立监狱的囚犯中爆发了入侵性粘质沙雷氏菌疫情

期刊:Emerging Infectious Diseases
影响因子:6.6
doi:10.3201/eid3013.230801
Kamali, Amanda; Ferguson, Donna; Dowless, Heather; Ortiz, Nancy; Mukhopadhyay, Rituparna; Schember, Cassandra; Lunsford, Rawni; Hutchinson, Justine; Scherer, Marlena; Crandall, John; Bauer, Heidi; Yu, Alexander; Kimura, Akiko
发表日期：2024
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Serratia marcescens Outbreak at a Correctional Facility: Environmental Sampling, Laboratory Analyses and Genomic Characterization to Assess Sources and Persistence

监狱设施中粘质沙雷氏菌暴发：环境采样、实验室分析和基因组表征以评估来源和持久性

期刊:International Journal of Environmental Research and Public Health
影响因子:
doi:10.3390/ijerph20176709
Ferguson, Donna; Ryder, Rahil; Lunsford, Rawni; Dash, Arie; Kamali, Amanda; Kimura, Akiko; Crandall, John; Mukhopadhyay, Rituparna; Dowless, Heather; Ortiz, Nancy; Jue, Nathaniel K
发表日期：2023
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Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models

检查点激酶 1 抑制剂 Prexasertib 作为单一药物或化学增强剂对一系列临床前儿科肿瘤模型的广谱活性

期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-18-2728
Caitlin D Lowery, Michele Dowless, Matthew Renschler, Wayne Blosser, Alle B VanWye, Jennifer R Stephens, Philip W Iversen, Aimee Bence Lin, Richard P Beckmann, Kateryna Krytska, Kristina A Cole, John M Maris, Douglas S Hawkins, Brian P Rubin, Raushan T Kurmasheva, Peter J Houghton, Richard Gorlick, 
信号转导
肿瘤
Checkpoint
发表日期：2019
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Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy

抗 VEGFR2 疗法可延缓临床前儿童肿瘤模型的生长并增强化疗的抗肿瘤活性

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.27148
Caitlin D Lowery, Wayne Blosser, Michele Dowless, Matthew Renschler, Lisa V Perez, Jennifer Stephens, Bronislaw Pytowski, Heather Wasserstrom, Louis F Stancato, Beverly Falcon
肿瘤
WB
发表日期：2019
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Abemaciclib Is Active in Preclinical Models of Ewing Sarcoma via Multipronged Regulation of Cell Cycle, DNA Methylation, and Interferon Pathway Signaling

Abemaciclib 通过多管齐下调节细胞周期、DNA 甲基化和干扰素通路信号传导，在尤文氏肉瘤临床前模型中发挥活性

期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-18-1256
Michele Dowless, Caitlin D Lowery, Terry Shackleford, Matthew Renschler, Jennifer Stephens, Robert Flack, Wayne Blosser, Simone Gupta, Julie Stewart, Yue Webster, Jack Dempsey, Alle B VanWye, Philip Ebert, Philip Iversen, Jonathan B Olsen, Xueqian Gong, Sean Buchanan, Peter Houghton, Louis Stancato
信号转导
表观遗传
其它细胞
DNA甲基化
Epigenetics
发表日期：2018
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Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib

激活 D 型细胞周期蛋白的基因组畸变与对 CDK4 和 CDK6 抑制剂 Abemaciclib 的敏感性增强有关

期刊:Cancer Cell
影响因子:48.8
doi:10.1016/j.ccell.2017.11.006
Xueqian Gong, Lacey M Litchfield, Yue Webster, Li-Chun Chio, Swee Seong Wong, Trent R Stewart, Michele Dowless, Jack Dempsey, Yi Zeng, Raquel Torres, Karsten Boehnke, Cecilia Mur, Carlos Marugán, Carmen Baquero, Chunping Yu, Steven M Bray, Isabella H Wulur, Chen Bi, Shaoyou Chu, Hui-Rong Qian, Phili
细胞生物学
其它细胞
发表日期：2017
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LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer

LY3009120 是一种 panRAF 抑制剂，在 BRAF 和 KRAS 突变的结肠直肠癌临床前模型中具有显著的抗肿瘤活性

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.14002
Eliza Vakana, Susan Pratt, Wayne Blosser, Michele Dowless, Nicholas Simpson, Xiu-Juan Yuan, Susan Jaken, Jason Manro, Jennifer Stephens, Youyan Zhang, Lysiane Huber, Sheng-Bin Peng, Louis F Stancato
肿瘤
肠癌
ICC-IF
IF
WB
c-Raf
发表日期：2017
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Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic Malignancies

完全人源化抗 CXCR4 抗体 LY2624587 抑制 CXCR4 可诱导血液系统恶性肿瘤细胞凋亡

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0150585
Sheng-Bin Peng, Xiaoyi Zhang, Donald Paul, Lisa M Kays, Ming Ye, Peter Vaillancourt, Michele Dowless, Louis F Stancato, Julie Stewart, Mark T Uhlik, Haiyan Long, Shaoyou Chu, Victor H Obungu
信号转导
细胞生物学
肿瘤
肿瘤细胞
Apoptosis
Human
发表日期：2016
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Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F

JAK2V617F 小分子酪氨酸激酶抑制剂 LY2784544 的发现和表征

期刊:Blood Cancer Journal
影响因子:12.9
doi:10.1038/bcj.2013.6
L Ma, J R Clayton, R A Walgren, B Zhao, R J Evans, M C Smith, K M Heinz-Taheny, E L Kreklau, L Bloem, C Pitou, W Shen, J M Strelow, C Halstead, M E Rempala, S Parthasarathy, J R Gillig, L J Heinz, H Pei, Y Wang, L F Stancato, M S Dowless, P W Iversen, T P Burkholder
信号转导
JAK/STAT
发表日期：2013
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A BMP7 variant inhibits the tumorigenic potential of glioblastoma stem-like cells

BMP7变体抑制胶质母细胞瘤干细胞样细胞的致瘤潜能

期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/cdd.2012.44
Tate, C M; Pallini, R; Ricci-Vitiani, L; Dowless, M; Shiyanova, T; D'Alessandris, G Q; Morgante, L; Giannetti, S; Larocca, L M; di Martino, S; Rowlinson, S W; De Maria, R; Stancato, L
细胞生物学
发育与干细胞
干细胞
发表日期：2012
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