Downes C Peter相关文献与解析，生知库 | 链接生命科学的每一步

The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2

通过激活含有Src同源结构域2的肌醇多磷酸5-磷酸酶2（SHIP2）来控制磷脂酰肌醇3,4-二磷酸的浓度。

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BJ20070558

Batty, Ian H; van der Kaay, Jeroen; Gray, Alex; Telfer, Joan F; Dixon, Miles J; Downes, C Peter

SHIP2

发表日期：2007

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PTEN is destabilized by phosphorylation on Thr366.

PTEN 在 Thr366 位点磷酸化后不稳定

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BJ20061837

Maccario Helene, Perera Nevin M, Davidson Lindsay, Downes C Peter, Leslie Nick R

A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells

下丘脑细胞系和胰岛β细胞中通过PTEN抑制介导的新型瘦素信号通路

期刊:EMBO Journal

影响因子:8.3

doi:10.1038/sj.emboj.7601118

Ning, Ke; Miller, Lisa C; Laidlaw, Hilary A; Burgess, Laura A; Perera, Nevin M; Downes, C Peter; Leslie, Nick R; Ashford, Michael L J

PTEN function: how normal cells control it and tumour cells lose it

PTEN功能：正常细胞如何控制它，以及肿瘤细胞如何失去它

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BJ20040825

Leslie, Nick R; Downes, C Peter

Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1

肌醇磷脂通过促进Tiam1与质膜的结合以及调节Rac1上的GDP/GTP交换来调控鸟嘌呤核苷酸交换因子Tiam1。

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BJ20040916

Fleming, Ian N; Batty, Ian H; Prescott, Alan R; Gray, Alex; Kular, Gursant S; Stewart, Hazel; Downes, C Peter

信号转导

发表日期：2004

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A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

磷脂酰肌醇3-激酶的p110δ亚基在B细胞发育和活化中起着至关重要的作用

期刊:Journal of Experimental Medicine

影响因子:10.6

doi:10.1084/jem.20020805

Clayton, Elizabeth; Bardi, Giuseppe; Bell, Sarah E; Chantry, David; Downes, C Peter; Gray, Alexander; Humphries, Lisa A; Rawlings, David; Reynolds, Helen; Vigorito, Elena; Turner, Martin

Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1.

利用磷脂酶 C delta1 的 pleckstrin 同源结构域对磷脂酰肌醇 4,5-二磷酸进行亚细胞定位

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/0264-6021:3630657

Watt Stephen A, Kular Gursant, Fleming Ian N, Downes C Peter, Lucocq John M

细胞生物学

发表日期：2002

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PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration

PTEN在细胞迁移调控中发挥PtdIns(3,4,5)P(3)依赖性和非依赖性作用

The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2

通过激活含有Src同源结构域2的肌醇多磷酸5-磷酸酶2（SHIP2）来控制磷脂酰肌醇3,4-二磷酸的浓度。

PTEN is destabilized by phosphorylation on Thr366.

PTEN 在 Thr366 位点磷酸化后不稳定

A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells

下丘脑细胞系和胰岛β细胞中通过PTEN抑制介导的新型瘦素信号通路

PTEN function: how normal cells control it and tumour cells lose it

PTEN功能：正常细胞如何控制它，以及肿瘤细胞如何失去它

Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1

肌醇磷脂通过促进Tiam1与质膜的结合以及调节Rac1上的GDP/GTP交换来调控鸟嘌呤核苷酸交换因子Tiam1。

A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

磷脂酰肌醇3-激酶的p110δ亚基在B细胞发育和活化中起着至关重要的作用

Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1.

利用磷脂酶 C delta1 的 pleckstrin 同源结构域对磷脂酰肌醇 4,5-二磷酸进行亚细胞定位