日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AI-based discovery and cryoEM structural elucidation of a K(ATP) channel pharmacochaperone

基于人工智能的K(ATP)通道药理伴侣蛋白的发现和冷冻电镜结构解析

Elsheikh, Assmaa; Driggers, Camden M; Truong, Ha H; Yang, Zhongying; Allen, John; Henriksen, Niel M; Walczewska-Szewc, Katarzyna; Shyng, Show-Ling

Dynamic duo: Kir6 and SUR in K(ATP) channel structure and function

黄金搭档:K(ATP)通道结构和功能中的Kir6和SUR

Patton, Bruce L; Zhu, Phillip; ElSheikh, Assmaa; Driggers, Camden M; Shyng, Show-Ling

Structure of an open K (ATP) channel reveals tandem PIP (2) binding sites mediating the Kir6.2 and SUR1 regulatory interface

开放的K(ATP)通道的结构揭示了串联的PIP(2)结合位点,这些位点介导了Kir6.2和SUR1的调控界面。

Driggers, Camden M; Kuo, Yi-Ying; Zhu, Phillip; ElSheikh, Assmaa; Shyng, Show-Ling

Mechanistic insights on KATP channel regulation from cryo-EM structures.

从冷冻电镜结构中揭示KATP通道调控的机制

Driggers Camden M, Shyng Show-Ling

Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K(ATP) Channel.

哺乳动物胰腺K(ATP)通道的配体介导结构动力学

Sung Min Woo, Driggers Camden M, Mostofian Barmak, Russo John D, Patton Bruce L, Zuckerman Daniel M, Shyng Show-Ling

Vascular K(ATP) channel structural dynamics reveal regulatory mechanism by Mg-nucleotides

血管K(ATP)通道结构动力学揭示Mg核苷酸的调控机制

Sung, Min Woo; Yang, Zhongying; Driggers, Camden M; Patton, Bruce L; Mostofian, Barmak; Russo, John D; Zuckerman, Daniel M; Shyng, Show-Ling

Production and purification of ATP-sensitive potassium channel particles for cryo-electron microscopy

用于冷冻电镜的ATP敏感钾通道颗粒的制备和纯化

Driggers, Camden M; Shyng, Show-Ling

Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection

通过反向选择提高容许型氨酰tRNA合成酶对目标氨基酸的选择性

Sungwienwong, Itthipol; Hostetler, Zachary M; Blizzard, Robert J; Porter, Joseph J; Driggers, Camden M; Mbengi, Lea Z; Villegas, José A; Speight, Lee C; Saven, Jeffery G; Perona, John J; Kohli, Rahul M; Mehl, Ryan A; Petersson, E James

Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase

基于结构的哺乳动物半胱氨酸双加氧酶中Cys-Tyr交联和抑制剂识别机制研究

Driggers, Camden M; Kean, Kelsey M; Hirschberger, Lawrence L; Cooley, Richard B; Stipanuk, Martha H; Karplus, P Andrew