日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer

mTORC2信号通路驱动胰腺癌的发生发展

Driscoll, David R; Karim, Saadia A; Sano, Makoto; Gay, David M; Jacob, Wright; Yu, Jun; Mizukami, Yusuke; Gopinathan, Aarthi; Jodrell, Duncan I; Evans, T R Jeffry; Bardeesy, Nabeel; Hall, Michael N; Quattrochi, Brian J; Klimstra, David S; Barry, Simon T; Sansom, Owen J; Lewis, Brian C; Morton, Jennifer P

Activation of WNT/β-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61

WNT/β-catenin信号通路的激活通过上调Cyr61增强胰腺癌的发展和恶性潜能

Sano, Makoto; Driscoll, David R; DeJesus-Monge, Wilfredo E; Quattrochi, Brian; Appleman, Victoria A; Ou, Jianhong; Zhu, Lihua Julie; Yoshida, Nao; Yamazaki, Shintaro; Takayama, Tadatoshi; Sugitani, Masahiko; Nemoto, Norimichi; Klimstra, David S; Lewis, Brian C

Activated wnt signaling in stroma contributes to development of pancreatic mucinous cystic neoplasms

基质中激活的Wnt信号通路促进胰腺黏液性囊性肿瘤的发生发展。

Sano, Makoto; Driscoll, David R; De Jesus-Monge, Wilfredo E; Klimstra, David S; Lewis, Brian C

Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas

食管和胰腺腺癌中表皮生长因子受体激酶结构域突变

Kwak, Eunice L; Jankowski, Janusz; Thayer, Sarah P; Lauwers, Gregory Y; Brannigan, Brian W; Harris, Patricia L; Okimoto, Ross A; Haserlat, Sara M; Driscoll, David R; Ferry, David; Muir, Beth; Settleman, Jeff; Fuchs, Charles S; Kulke, Matthew H; Ryan, David P; Clark, Jeff W; Sgroi, Dennis C; Haber, Daniel A; Bell, Daphne W

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib.

EGF 受体的不可逆抑制剂可以克服对吉非替尼的获得性耐药性

Kwak Eunice L, Sordella Raffaella, Bell Daphne W, Godin-Heymann Nadia, Okimoto Ross A, Brannigan Brian W, Harris Patricia L, Driscoll David R, Fidias Panos, Lynch Thomas J, Rabindran Sridhar K, McGinnis John P, Wissner Allan, Sharma Sreenath V, Isselbacher Kurt J, Settleman Jeffrey, Haber Daniel A