日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo Activity

发现具有强效体内活性的苯并内酰胺类IRAK4抑制剂

Rajapaksa, Naomi S; Gobbi, Alberto; Drobnick, Joy; Do, Steven; Kolesnikov, Aleksandr; Liang, Jun; Chen, Yongsheng; Sujatha-Bhaskar, Swathi; Huang, Zhiyu; Brightbill, Hans; Francis, Ross; Yu, Christine; Choo, Edna F; DeMent, Kevin; Ran, Yingqing; An, Le; Emson, Claire; Maher, Jonathan; Wai, John; McKenzie, Brent S; Lupardus, Patrick J; Zarrin, Ali A; Kiefer, James R; Bryan, Marian C

Improving Responsiveness to Patient Phone Calls: A Pilot Study

提高对患者电话的响应速度:一项试点研究

O'Brien, Lisa K; Drobnick, Patricia; Gehman, Mary; Hollenbeak, Christopher; Iantosca, Mark R; Luchs, Sherri; Manning, Maureen; Palm, Susan K; Potochny, John; Ritzman, Angela; Tetro-Viozzi, Jennie; Trauger, Mary; Armstrong, April D

Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR

发现临床开发候选药物GDC-0084,一种可穿透血脑屏障的PI3K和mTOR抑制剂

Heffron, Timothy P; Ndubaku, Chudi O; Salphati, Laurent; Alicke, Bruno; Cheong, Jonathan; Drobnick, Joy; Edgar, Kyle; Gould, Stephen E; Lee, Leslie B; Lesnick, John D; Lewis, Cristina; Nonomiya, Jim; Pang, Jodie; Plise, Emile G; Sideris, Steve; Wallin, Jeffrey; Wang, Lan; Zhang, Xiaolin; Olivero, Alan G

Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety

选择性 PAK1 抑制剂 G-5555 的设计:通过采用非传统低 pK 极性部分来改善性能

Chudi O Ndubaku, James J Crawford, Joy Drobnick, Ignacio Aliagas, David Campbell, Ping Dong, Laura M Dornan, Sergio Duron, Jennifer Epler, Lewis Gazzard, Christopher E Heise, Klaus P Hoeflich, Diana Jakubiak, Hank La, Wendy Lee, Baiwei Lin, Joseph P Lyssikatos, Jasna Maksimoska, Ronen Marmorstein, L