日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Thymine DNA glycosylase binds to R-loops and excises 5-formyl and 5-carboxyl cytosine from DNA/RNA hybrids

胸腺嘧啶DNA糖基化酶与R环结合,并从DNA/RNA杂交体中切除5-甲酰基和5-羧基胞嘧啶。

Zhu, Baiyu; Pidugu, Lakshmi S; Cook, Mary E; Nie, Xinyu Y; Amarasekara, E A P Tharaka; Menet, Jerome S; Drohat, Alexander C; Sczepanski, Jonathan T

Observing nucleotide flipping in DNA using indirect 2'-F nucleotide probes and 19F NMR

利用间接的2'-F核苷酸探针和19F NMR观察DNA中的核苷酸翻转

Pidugu, Lakshmi S; Gustafson, Erin E; Servius, Hardler W; Cook, Mary E; Lee, Nina C; Varney, Kristen M; Drohat, Alexander C

Characterizing the excision of 7,8-dihydro-8-oxoadenine by thymine DNA glycosylase

胸腺嘧啶DNA糖苷酶对7,8-二氢-8-氧代腺嘌呤的切除特性分析

Servius, Hardler W; Drohat, Alexander C

Thymine DNA Glycosylase Binds to R-Loops and Excises 5-Formyl and 5-Carboxyl Cytosine from DNA/RNA Hybrids.

胸腺嘧啶 DNA 糖基化酶与 R 环结合,从 DNA/RNA 杂交体中切除 5-甲酰基胞嘧啶和 5-羧基胞嘧啶

Zhu Baiyu, Pidugu Lakshmi S, Cook Mary E, Nie Xinyu Y, Amarasekara E A P Tharaka, Menet Jerome S, Drohat Alexander C, Sczepanski Jonathan T

Sumoylation of thymine DNA glycosylase impairs productive binding to substrate sites in DNA

胸腺嘧啶DNA糖苷酶的SUMO化会损害其与DNA底物位点的有效结合。

Pidugu, Lakshmi S; Servius, Hardler W; Espinosa, Kurt B; Cook, Mary E; Varney, Kristen M; Drohat, Alexander C

Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase

阐明SUMO化对胸腺嘧啶DNA糖苷酶底物结合和催化作用的影响

Coey, Christopher T; Drohat, Alexander C

Kinetic Methods for Studying DNA Glycosylases Functioning in Base Excision Repair

用于研究碱基切除修复中DNA糖基化酶功能的动力学方法

Coey, Christopher T; Drohat, Alexander C

Role of Base Excision "Repair" Enzymes in Erasing Epigenetic Marks from DNA

碱基切除“修复”酶在清除DNA表观遗传标记中的作用

Drohat, Alexander C; Coey, Christopher T

Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA

胸腺嘧啶DNA糖基化酶对它从DNA中移除的核碱基的亲和力可以忽略不计。

Malik, Shuja S; Coey, Christopher T; Varney, Kristen M; Pozharski, Edwin; Drohat, Alexander C

Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+ cofactor

人类脱嘌呤/脱嘧啶核酸内切酶 1 及其必需的 Mg2+ 辅因子的结构

Manvilla, Brittney A; Pozharski, Edwin; Toth, Eric A; Drohat, Alexander C