日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Wnt/β-catenin activation by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary basal cell adenoma.

FBXW11 和 CTNNB1 热点突变相互排斥,激活 Wnt/β-catenin,从而驱动唾液腺基底细胞腺瘤的发生

Wong Kim, Bishop Justin A, Weinreb Ilan, Motta Marialetizia, Del Castillo Velasco-Herrera Martin, Bellacchio Emanuele, Ferreira Ingrid, van der Weyden Louise, Boccacino Jacqueline M, Lauri Antonella, Rotundo Giovannina, Ciolfi Andrea, Cheema Saamin, Olvera-León Rebeca, Offord Victoria, Droop Alastair, Vermes Ian, Allgäuer Michael, Hyrcza Martin, Anderson Elizabeth, Smith Katie, de Saint Aubain Nicolas, Mogler Carolin, Stenzinger Albrecht, Arends Mark J, Brenn Thomas, Tartaglia Marco, Adams David J

Comprehensive mutational profiling identifies new driver events in cutaneous leiomyosarcoma

全面的突变谱分析揭示了皮肤平滑肌肉瘤中的新驱动事件

van der Weyden, Louise; Del Castillo Velasco-Herrera, Martin; Cheema, Saamin; Wong, Kim; Boccacino, Jacqueline M; Offord, Victoria; Droop, Alastair; Jones, David R A; Vermes, Ian; Anderson, Elizabeth; Hardy, Claire; de Saint Aubain, Nicolas; Ferguson, Peter M; Clarke, Emily L; Merchant, William; Mogler, Carolin; Frew, Derek; Harms, Paul W; Monteagudo, Carlos; Billings, Steven D; Arends, Mark J; Ferreira, Ingrid; Brenn, Thomas; Adams, David J

Exploration of the mutational landscape of cutaneous leiomyoma confirms FH as a driver gene and identifies targeting purine metabolism as a potential therapeutic strategy

对皮肤平滑肌瘤突变图谱的探索证实了FH是驱动基因,并确定靶向嘌呤代谢是一种潜在的治疗策略。

van der Weyden, Louise; Del Castillo Velasco-Herrera, Martin; Cheema, Saamin; Wong, Kim; Boccacino, Jacqueline M; Vermes, Ian; Offord, Victoria; Droop, Alastair; Jones, David R A; Anderson, Elizabeth; Hardy, Claire; de Saint Aubain, Nicolas; Ferguson, Peter M; Mogler, Carolin; Rajan, Neil; Frew, Derek; Harms, Paul W; Billings, Steven D; Schatton, Désirée; Segarra-Mondejar, Marc; Arends, Mark J; Ferreira, Ingrid; Brenn, Thomas; Frezza, Christian; Adams, David J

Killer toxin K28 resistance in yeast relies on COG complex-mediated trafficking of the defence factor Ktd1

酵母对杀伤毒素K28的抗性依赖于COG复合物介导的防御因子Ktd1的运输。

Laidlaw, Kamilla M E; Nadir, Hatwan H; Milburn, Amy; Xelhuantzi, Martha S C; Stanislovas, Justas; Droop, Alastair P; MacDonald, Sandy; Andreev, Ilya; Leech, Andrew; Ungar, Daniel; Sadhu, Meru J; MacDonald, Chris

Defining novel causal SNPs and linked phenotypes at melanoma-associated loci

确定黑色素瘤相关基因位点上的新型致病性单核苷酸多态性(SNP)及其相关表型

Castaneda-Garcia, Carolina; Iyer, Vivek; Nsengimana, Jérémie; Trower, Adam; Droop, Alastair; Brown, Kevin M; Choi, Jiyeon; Zhang, Tongwu; Harland, Mark; Newton-Bishop, Julia A; Bishop, D Timothy; Adams, David J; Iles, Mark M; Robles-Espinoza, Carla Daniela

ETS transcription factor ELF3 (ESE-1) is a cell cycle regulator in benign and malignant prostate

ETS转录因子ELF3(ESE-1)是良性和恶性前列腺细胞的细胞周期调节因子

Archer, Leanne K; Frame, Fiona M; Walker, Hannah F; Droop, Alastair P; McDonald, Georgina L K; Kucko, Samuel; Berney, Daniel M; Mann, Vincent M; Simms, Matthew S; Maitland, Norman J

Phenotype-independent DNA methylation changes in prostate cancer

前列腺癌中与表型无关的DNA甲基化改变

Pellacani, Davide; Droop, Alastair P; Frame, Fiona M; Simms, Matthew S; Mann, Vincent M; Collins, Anne T; Eaves, Connie J; Maitland, Norman J

qsubsec: a lightweight template system for defining sun grid engine workflows

qsubsec:一个用于定义 Sun Grid Engine 工作流程的轻量级模板系统

Droop, Alastair P

Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance.

视黄酸和雄激素受体共同作用,实现了对人类前列腺转谷氨酰胺酶表达的组织特异性控制:一种具有更广泛意义的新型调控网络

Rivera-Gonzalez Guillermo C, Droop Alastair P, Rippon Helen J, Tiemann Katrin, Pellacani Davide, Georgopoulos Lindsay J, Maitland Norman J

Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions

人类前列腺癌干细胞的基因表达谱分析揭示了其促炎表型以及细胞外基质相互作用的重要性。

Birnie, Richard; Bryce, Steven D; Roome, Claire; Dussupt, Vincent; Droop, Alastair; Lang, Shona H; Berry, Paul A; Hyde, Catherine F; Lewis, John L; Stower, Michael J; Maitland, Norman J; Collins, Anne T