日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reduced Function of the Adaptor SH2B3 Promotes T1D via Altered Cytokine-Regulated, T-Cell-Intrinsic Immune Tolerance

衔接蛋白SH2B3功能降低通过改变细胞因子调节的T细胞固有免疫耐受性促进1型糖尿病的发生

Watson, Taylor K; Rosen, Aaron B I; Drow, Travis; Medjo, Jacob A; MacQuivey, Matthew A; Ge, Yan; Liggitt, H Denny; Grosvenor, Dane A; Dill-McFarland, Kimberly A; Altman, Matthew C; Concannon, Patrick J; Buckner, Jane H; Rawlings, David J; Allenspach, Eric J

GNTI-122: an autologous antigen-specific engineered Treg cell therapy for type 1 diabetes

GNTI-122:一种用于治疗1型糖尿病的自体抗原特异性工程化Treg细胞疗法

Gene I Uenishi ,Marko Repic ,Jennifer Y Yam ,Ashley Landuyt ,Priya Saikumar-Lakshmi ,Tingxi Guo ,Payam Zarin ,Martina Sassone-Corsi ,Adam Chicoine ,Hunter Kellogg ,Martina Hunt ,Travis Drow ,Ritika Tewari ,Peter J Cook ,Soo Jung Yang ,Karen Cerosaletti ,Darius Schweinoch ,Benjamin Guiastrennec ,Eddie James ,Chandra Patel ,Tiffany F Chen ,Jane H Buckner ,David J Rawlings ,Thomas J Wickham ,Karen T Mueller

Activated PI3Kδ Specifically Perturbs Mouse Regulatory T Cell Homeostasis and Function Leading to Immune Dysregulation

活化的PI3Kδ特异性地扰乱小鼠调节性T细胞的稳态和功能,导致免疫失调

Singh, Akhilesh K; Al Qureshah, Fahd; Drow, Travis; Hou, Baidong; Rawlings, David J

A chemically inducible IL-2 receptor signaling complex allows for effective in vitro and in vivo selection of engineered CD4+ T cells

化学诱导的 IL-2 受体信号复合物可有效在体内和体外筛选工程化 CD4+ T 细胞

Peter J Cook, Su Jung Yang, Gene I Uenishi, Annaiz Grimm, Samuel E West, Li-Jie Wang, Chester Jacobs, Andrea Repele, Travis Drow, Ahmad Boukhris, Noelle P Dahl, Karen Sommer, Andrew M Scharenberg, David J Rawlings

Corrigendum to "Islet allografts expressing a PD-L1 and IDO fusion protein evade immune rejection and reverse preexisting diabetes in immunocompetent mice without systemic immunosuppression" [American Journal of Transplantation (2022) 2571-2585]

对“表达 PD-L1 和 IDO 融合蛋白的胰岛同种异体移植可逃避免疫排斥,并在免疫功能正常的鼠中逆转已存在的糖尿病,而无需全身免疫抑制”的更正[美国移植杂志 (2022) 2571-2585]

Paul, Pradyut K; Das, Rahul; Drow, Travis; Nylen, Emily A; Henrique de Souza, Arnaldo; Wang, Zunyi; Wood, Michael W; Davis, Dawn B; Bjorling, Dale E; Galipeau, Jacques

Activated PI3Kδ specifically perturbs mouse Treg homeostasis and function leading to immune dysregulation

活化的PI3Kδ特异性地扰乱小鼠Treg细胞的稳态和功能,导致免疫失调。

Singh, Akhilesh K; Qureshah, Fahd Al; Drow, Travis; Hou, Baidong; Rawlings, David J

Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models

胰岛特异性工程化 Treg 在 1 型糖尿病模型中表现出强大的抗原特异性和旁观者免疫抑制

Soo Jung Yang, Akhilesh K Singh, Travis Drow, Tori Tappen, Yuchi Honaker, Fariba Barahmand-Pour-Whitman, Peter S Linsley, Karen Cerosaletti, Kelsey Mauk, Yufei Xiang, Jessica Smith, Emma Mortensen, Peter J Cook, Karen Sommer, Iram Khan, Denny Liggitt, David J Rawlings, Jane H Buckner

Islet allografts expressing a PD-L1 and IDO fusion protein evade immune rejection and reverse preexisting diabetes in immunocompetent mice without systemic immunosuppression

表达PD-L1和IDO融合蛋白的胰岛同种异体移植可以避免免疫排斥,并在免疫功能正常的小鼠体内逆转已存在的糖尿病,而无需全身性免疫抑制。

Paul, Pradyut K; Das, Rahul; Drow, Travis; Nylen, Emily A; de Souza, Arnaldo Henrique; Wang, Zunyi; Wood, Michael W; Davis, Dawn B; Bjorling, Dale E; Galipeau, Jacques

Pancreatic Stellate Cells Prolong Ex Vivo Islet Viability and Function and Improve Engraftment

胰腺星状细胞延长体外胰岛活力和功能并改善植入

Pradyut K Paul, Rahul Das, Travis J Drow, Arnaldo H de Souza, Appakalai N Balamurugan, Dawn Belt Davis, Jacques Galipeau

Comparison of the Lumac and Monolight systems for detection of bacteriuria by bioluminescence

利用生物发光法比较 Lumac 和 Monolight 系统检测菌尿症

Drow, D L; Baum, C H; Hirschfield, G