日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ectopic, hepatic GLP-1R agonism enhances the weight loss efficacy of GLP-1 analogues

异位肝脏GLP-1R激动作用可增强GLP-1类似物的减肥效果。

Douros, Jonathan D; Capozzi, Megan; Novikoff, Aaron; Mokrosinski, Jacek; DuBois, Barent; Stock, Joseph; Rohlfs, Rebecca; Anderson, Mikayla; Jedrzejcyk, Dominika J; Poulsen, Svend; Blenke, Erik Oude; Dago, Tomas; Huus, Kasper; Nørby, Peder L; Kobberup, Sune; Rivir, Marita; Sorrell, Joyce; Mowery, Stephanie A; Drucker, Daniel J; D'Alessio, David A; Campbell, Jonathan E; Müller, Timo D; Perez-Tilve, Diego; Finan, Brian; Knerr, Patrick J

Loss of GLP-2R signaling in Glp2r(-/-) mice increases the long-term severity of graft versus host disease

Glp2r(-/-)小鼠中GLP-2R信号传导的缺失会加重移植物抗宿主病的长期严重程度。

Yusta, Bernardo; Wong, Chi Kin; Matthews, Dianne; Koehler, Jacqueline A; Baggio, Laurie L; Drucker, Daniel J

Semaglutide reduces murine blood pressure through the vascular smooth muscle GLP-1 receptor

司美格鲁肽通过血管平滑肌GLP-1受体降低小鼠血压

Medak, Kyle D; Koehler, Jacqueline A; Baggio, Laurie L; Gonzalez-Rellan, Maria J; Wong, Chi Kin; Cao, Xiemin; Rao, Vivikta; Kao, Sean; Cui, Yu; Fu, Jiayi; Liaw, Easton; Kabir, M Golam; Zhang, Jie; Wei, Jin; Drucker, Daniel J

Glucagon receptor signaling is indispensable for the healthspan effects of caloric restriction in aging male mice

胰高血糖素受体信号传导对于热量限制延长老年雄性小鼠的健康寿命至关重要。

Bruner, Kassandra R; Byington, Isabella R; Marx, Tyler J; Vasileva, Anastasiia; Fletcher, Temara; Ghimire, Susma; Zappia, India J; Shaju, Yashika; Zeng, Janan; Wachsmuth, Hallie R; Carlyon, Thadeus W; Besselsen, David G; Drucker, Daniel J; Duca, Frank A; Stern, Jennifer H

Glucagon-like peptide-1 receptor signaling deficiency exacerbates hematopoietic stem cell graft rejection in mice

胰高血糖素样肽-1受体信号传导缺陷会加剧小鼠造血干细胞移植排斥反应。

Rusznak, Mark; Sierra-Hernandez, Daniela; Dupuy, Catherine; Toki, Shinji; Wu, Ashley Y; Rao, Uttam; Abney, Masako; Zhang, Jian; Hu, Qianni; Warren, Christian M; Drucker, Daniel J; Niswender, Kevin D; Engelhardt, Brian; Kim, Tae Kon; Gibson-Corley, Katherine N; Cahill, Katherine N; Cooke, Kenneth R; Peebles, R Stokes Jr

Antiinflammatory actions of glucagon-like peptide-1-based therapies beyond metabolic benefits

胰高血糖素样肽-1疗法的抗炎作用及其代谢益处之外的其他益处

Wong, Chi Kin; Drucker, Daniel J

The expanding benefits of GLP-1 medicines

GLP-1药物的益处日益扩大

Gonzalez-Rellan, Maria J; Drucker, Daniel J

Glucagon-like peptide-1 medicines in neurological and psychiatric disorders

胰高血糖素样肽-1类药物在神经系统和精神疾病中的应用

Fang, Susanna; Cui, Fiona; Drucker, Daniel J

A peek into the pipeline: Expert views on emerging therapies

一窥研发管线:专家对新兴疗法的看法

Dewachter, Ilse; Höglinger, Günter U; Drucker, Daniel J; Brown, Christine E; Martin, Roland; Chang, Anne Bernadette; Chotirmall, Sanjay Haresh; Qi, Xiaolong; Shaw, Pamela

Therapeutic Targeting of the GIP Receptor-Revisiting the Controversies

GIP受体靶向治疗——重新审视争议

Campbell, Jonathan E; Drucker, Daniel J