日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cellular senescence in liver diseases: From molecular drivers to therapeutic targeting

肝脏疾病中的细胞衰老:从分子驱动因素到治疗靶点

Du, Kuo; Umbaugh, David S; Ren, Niansheng; Diehl, Anna Mae

Zinc-dependent RNA-binding protein controls hepatocyte senescence and recovery from alcohol-related liver failure

锌依赖性RNA结合蛋白调控肝细胞衰老和酒精性肝衰竭的恢复。

Dutta, Rajesh Kumar; Du, Kuo; Ren, Niansheng; Umbaugh, David S; Oh, Seh-Hoon; Wang, Liuyang; Kalsotra, Auinash; Blackshear, Perry J; Diehl, Anna Mae

WSTF nuclear autophagy regulates chronic but not acute inflammation.

WSTF 核自噬调节慢性炎症,但不调节急性炎症。

Wang Yu, Eapen Vinay V, Liang Yaosi, Kournoutis Athanasios, Sherman Marc Samuel, Xu Yanxin, Onorati Angelique, Li Xianting, Zhou Xiaoting, Corey Kathleen E, Du Kuo, Cabral Burkard Ana Maria, Ho Chia-Kang, Xie Jing, Zhang Hui, Maeso-Díaz Raquel, Ma Xinyi, Rieprecht Ulrike, O'Brien Tara, Cetinbas Murat, Wang Lu, Liu Jihe, Bretz Corey, Havas Aaron P, Zhou Zhuo, Ho Sui Shannan J, Saladi Srinivas Vinod, Sadreyev Ruslan I, Adams Peter D, Kingston Robert E, Diehl Anna Mae, Alman Benjamin, Goessling Wolfram, Yue Zhenyu, Wang Xiao-Fan, Johansen Terje, Dou Zhixun

Author Correction: Targeting senescent hepatocytes for treatment of metabolic dysfunction-associated steatotic liver disease and multi-organ dysfunction

作者更正:靶向衰老肝细胞治疗代谢功能障碍相关的脂肪肝和多器官功能障碍

Du, Kuo; Umbaugh, David S; Wang, Liuyang; Jun, Ji Hye; Dutta, Rajesh K; Oh, Seh Hoon; Ren, Niansheng; Zhang, Qiaojuan; Ko, Dennis C; Ferreira, Ana; Hill, Jon; Gao, Guannan; Pullen, Steven S; Jain, Vaibhav; Gregory, Simon; Abdelmalek, Manal F; Diehl, Anna Mae

Targeting senescent hepatocytes for treatment of metabolic dysfunction-associated steatotic liver disease and multi-organ dysfunction.

靶向衰老肝细胞治疗代谢功能障碍相关的脂肪肝疾病和多器官功能障碍

Du Kuo, Umbaugh David S, Wang Liuyang, Jun Ji Hye, Dutta Rajesh K, Oh Seh Hoon, Ren Niansheng, Zhang Qiaojuan, Ko Dennis C, Ferreira Ana, Hill Jon, Gao Guannan, Pullen Steven S, Jain Vaibhav, Gregory Simon, Abdelmalek Manal F, Diehl Anna Mae

Redefining senescence through hepatocyte fate changes in liver diseases

通过肝细胞命运改变重新定义肝脏疾病中的衰老

Umbaugh, David S; Diehl, Anna Mae; Du, Kuo

Aging promotes metabolic dysfunction-associated steatotic liver disease by inducing ferroptotic stress.

衰老通过诱导铁死亡应激促进代谢功能障碍相关的脂肪肝疾病。

Du Kuo, Wang Liuyang, Jun Ji Hye, Dutta Rajesh K, Maeso-Díaz Raquel, Oh Seh Hoon, Ko Dennis C, Diehl Anna Mae

A systemic effect for liver senescence

对肝脏衰老的系统性影响

Du, Kuo; Umbaugh, David Scott; Dutta, Rajesh Kumar; Diehl, Anna Mae

The senescence-associated secretome of Hedgehog-deficient hepatocytes drives MASLD progression

缺乏 Hedgehog 信号通路的肝细胞的衰老相关分泌组驱动 MASLD 的进展

Jun, Ji Hye; Du, Kuo; Dutta, Rajesh Kumar; Maeso-Diaz, Raquel; Oh, Seh Hoon; Wang, Liuyang; Gao, Guannan; Ferreira, Ana; Hill, Jon; Pullen, Steven S; Diehl, Anna Mae

Plasticity, heterogeneity, and multifunctionality of hepatic stellate cells in liver pathophysiology

肝星状细胞的可塑性、异质性和多功能性在肝脏病理生理学中的作用

Du, Kuo; Jun, Ji Hye; Dutta, Rajesh K; Diehl, Anna Mae