日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Engineered BMP2/BMP7 extracellular vesicles induce autocrine BMP release driving SMAD phosphorylation to promote bone formation.

工程化的 BMP2/BMP7 细胞外囊泡诱导自分泌 BMP 释放，驱动 SMAD 磷酸化，从而促进骨形成

期刊:npj Regenerative Medicine
影响因子:6.5
doi:10.1038/s41536-025-00405-2
Du Zeji, Rizzo Skylar A, Sarrafian Tiffany L, Bagwell Monique S, Mahlberg Ryan C, Amontree Ashley, Schiebel Paige, Tauferner Dinah M, LeBrasseur Zoe S, Witt Tyra A, Nagel Mary, Boyd Kyla A, De Vitto Humberto, Hillestad Matthew L, Stalboerger Paul G, Houdek Matthew T, Sierra Rafael J, Behfar Atta
细胞生物学
囊泡
磷酸化
发表日期：2025
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In vivo lentiviral vector gene therapy to cure hereditary tyrosinemia type 1 and prevent development of precancerous and cancerous lesions

利用体内慢病毒载体基因疗法治愈1型遗传性酪氨酸血症并预防癌前病变和癌变的发展

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-022-32576-7
Nicolas, Clara T; VanLith, Caitlin J; Hickey, Raymond D; Du, Zeji; Hillin, Lori G; Guthman, Rebekah M; Cao, William J; Haugo, Benjamin; Lillegard, Annika; Roy, Diya; Bhagwate, Aditya; O'Brien, Daniel; Kocher, Jean-Pierre; Kaiser, Robert A; Russell, Stephen J; Lillegard, Joseph B
微生物学
肿瘤
肿瘤免疫
发表日期：2022
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Autologous Gene and Cell Therapy Provides Safe and Long-Term Curative Therapy in A Large Pig Model of Hereditary Tyrosinemia Type 1

自体基因和细胞疗法在大型猪遗传性酪氨酸血症1型模型中提供安全且长期的治愈性治疗

期刊:Cell Transplantation
影响因子:3.2
doi:10.1177/0963689718814188
Hickey, Raymond D; Nicolas, Clara T; Allen, Kari; Mao, Shennen; Elgilani, Faysal; Glorioso, Jaime; Amiot, Bruce; VanLith, Caitlin; Guthman, Rebekah; Du, Zeji; Chen, Harvey; Harding, Cary O; Kaiser, Robert A; Nyberg, Scott L; Lillegard, Joseph B
细胞生物学
发表日期：2019
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Hepatotoxicity and Toxicology of In Vivo Lentiviral Vector Administration in Healthy and Liver-Injury Mouse Models

慢病毒载体体内给药在健康和肝损伤小鼠模型中的肝毒性和毒理学研究

期刊:Human Gene Therapy Clinical Development
影响因子:
doi:10.1089/humc.2018.249
Kaiser, Robert Allen; Nicolas, Clara Teresa; Allen, Kari Lynn; Chilton, Jennifer Anne; Du, Zeji; Hickey, Raymond Daniel; Lillegard, Joseph Benjamin
Mouse
发表日期：2019
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Curative Ex Vivo Hepatocyte-Directed Gene Editing in a Mouse Model of Hereditary Tyrosinemia Type 1

在1型遗传性酪氨酸血症小鼠模型中，体外肝细胞定向基因编辑的治愈性治疗

期刊:Human Gene Therapy
影响因子:4
doi:10.1089/hum.2017.252
VanLith, Caitlin; Guthman, Rebekah; Nicolas, Clara T; Allen, Kari; Du, Zeji; Joo, Dong Jin; Nyberg, Scott L; Lillegard, Joseph B; Hickey, Raymond D
细胞生物学
Mouse
发表日期：2018
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Lentiviral Vector-mediated Gene Therapy of Hepatocytes Ex Vivo for Autologous Transplantation in Swine.

利用慢病毒载体介导的体外肝细胞基因治疗进行猪自体移植

期刊:Jove-Journal of Visualized Experiments
影响因子:1
doi:10.3791/58399
Kaiser Robert A, Mao Shennen A, Glorioso Jaime, Amiot Bruce, Nicolas Clara T, Allen Kari L, Du Zeji, VanLith Caitlin J, Hickey Raymond D, Nyberg Scott L, Lillegard Joseph B
细胞生物学
Viral
细胞基因治疗
发表日期：2018
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A pig-to-mouse coronary artery transplantation model for investigating the pathogenicity of anti-pig antibody

利用猪-鼠冠状动脉移植模型研究抗猪抗体的致病性

期刊:Xenotransplantation
影响因子:4.1
doi:10.1111/xen.12198
Lin, Yi; Miyagi, Naoto; Byrne, Guerard W; Du, Zeji; Kogelberg, Heide; Gazi, Mozammel H; Tazelaar, Henry D; Wang, Chunsheng; McGregor, Christopher G A
发表日期：2015
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Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen

克隆和表达编码一种新的异种反应性抗原的猪β1,4 N-乙酰半乳糖胺转移酶

期刊:Xenotransplantation
影响因子:4.1
doi:10.1111/xen.12124
Byrne, Guerard W; Du, Zeji; Stalboerger, Paul; Kogelberg, Heide; McGregor, Christopher G A
发表日期：2014
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Human CD55 expression blocks hyperacute rejection and restricts complement activation in Gal knockout cardiac xenografts

人源CD55表达可阻断Gal基因敲除心脏异种移植中的超急性排斥反应并限制补体激活。

期刊:Transplantation
影响因子:5
doi:10.1097/TP.0b013e3182472850
McGregor, Christopher G A; Ricci, Davide; Miyagi, Naoto; Stalboerger, Paul G; Du, Zeji; Oehler, Elise A; Tazelaar, Henry D; Byrne, Guerard W
CD5
免疫排斥
Human
CD55
免疫/内分泌
发表日期：2012
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Changes in cardiac gene expression after pig-to-primate orthotopic xenotransplantation

猪到灵长类动物原位异种移植后心脏基因表达的变化

期刊:Xenotransplantation
影响因子:4.1
doi:10.1111/j.1399-3089.2010.00620.x
Byrne, Guerard W; Du, Zeji; Sun, Zhifu; Asmann, Yan W; McGregor, Christopher G A
发表日期：2011
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