日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins.

无尾目石房蛤毒素结合蛋白对石房蛤毒素同系物结合和中和的结构基础

Zakrzewska Sandra, Nixon Samantha A, Chen Zhou, Hajare Holly S, Park Elizabeth R, Mulcahy John V, Arlinghaus Kandis M, Neu Eduard, Konovalov Kirill, Provasi Davide, Leighfield Tod A, Filizola Marta, Du Bois J, Minor Daniel L Jr

A chemogenetic ligand-receptor pair for voltage-gated sodium channel subtype-selective inhibition

用于电压门控钠通道亚型选择性抑制的化学遗传配体-受体对

Park, Elizabeth R; Denomme, Nicholas; Hajare, Holly S; Du Bois, J

Saxiphilin functions as a 'toxin sponge' protein that counteracts the effects of saxitoxin poisoning

Saxiphilin 蛋白作为一种“毒素海绵”蛋白,能够抵消石房蛤毒素中毒的影响。

Nixon, Samantha A; Zakrzewska, Sandra; Jang, Seil; Huang, Keli; Bara, Anissa; Chen, Zhou; Goss, Daynen R; Park, Elizabeth R; Du Bois, J; Minor, Daniel L Jr

Schwann cell-secreted PGE(2) promotes sensory neuron excitability during development.

雪旺细胞分泌的 PGE(2) 在发育过程中促进感觉神经元的兴奋性

Kantarci Husniye, Elvira Pablo D, Thottumkara Arun P, O'Connell Emma M, Iyer Manasi, Donovan Lauren J, Dugan Micaela Quinn, Ambiel Nicholas, Granados Alejandro, Zeng Hong, Saw Nay L, Brosius Lutz Amanda, Sloan Steven A, Gray Erin E, Tran Khanh V, Vichare Aditi, Yeh Ashley K, Münch Alexandra E, Huber Max, Agrawal Aditi, Morri Maurizio, Zhong Haining, Shamloo Mehrdad, Anderson Thomas Anthony, Tawfik Vivianne L, Du Bois J, Zuchero J Bradley

Trifunctional Saxitoxin Conjugates for Covalent Labeling of Voltage-Gated Sodium Channels

用于电压门控钠通道共价标记的三功能石房蛤毒素缀合物

Finkelstein, Darren S; Du Bois, J

Author Correction: Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin

作者更正:光笼式石房蛤毒素对电压门控钠通道的精确时空控制

Elleman, Anna V; Devienne, Gabrielle; Makinson, Christopher D; Haynes, Allison L; Huguenard, John R; Du Bois, J

Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family

确定石房蛤毒素 (STX) 结合密码有助于发现和表征无尾目石房蛤毒素家族。

Chen, Zhou; Zakrzewska, Sandra; Hajare, Holly S; Alvarez-Buylla, Aurora; Abderemane-Ali, Fayal; Bogan, Maximiliana; Ramirez, Dave; O'Connell, Lauren A; Du Bois, J; Minor, Daniel L Jr

Discovery of Selective Inhibitors of Na(V)1.7 Templated on Saxitoxin as Therapeutics for Pain

以石房蛤毒素为模板发现选择性Na(V)1.7抑制剂作为疼痛治疗药物

Pajouhesh, Hassan; Delwig, Anton; Beckley, Jacob T; Klas, Sheri; Monteleone, Dennis; Zhou, Xiang; Luu, George; Du Bois, J; Hunter, John C; Mulcahy, John V

Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin

利用光笼式石房蛤毒素对电压门控钠通道进行精确的时空控制

Elleman, Anna V; Devienne, Gabrielle; Makinson, Christopher D; Haynes, Allison L; Huguenard, John R; Du Bois, J

Evidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on "toxin sponge" proteins

有证据表明,毒鸟和毒蛙的毒素抗性并非源于钠通道突变,而是可能依赖于“毒素海绵”蛋白。

Abderemane-Ali, Fayal; Rossen, Nathan D; Kobiela, Megan E; Craig, Robert A; Garrison, Catherine E; Chen, Zhou; Colleran, Claire M; O'Connell, Lauren A; Du Bois, J; Dumbacher, John P; Minor, Daniel L