日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ectopic, hepatic GLP-1R agonism enhances the weight loss efficacy of GLP-1 analogues

异位肝脏GLP-1R激动作用可增强GLP-1类似物的减肥效果。

Douros, Jonathan D; Capozzi, Megan; Novikoff, Aaron; Mokrosinski, Jacek; DuBois, Barent; Stock, Joseph; Rohlfs, Rebecca; Anderson, Mikayla; Jedrzejcyk, Dominika J; Poulsen, Svend; Blenke, Erik Oude; Dago, Tomas; Huus, Kasper; Nørby, Peder L; Kobberup, Sune; Rivir, Marita; Sorrell, Joyce; Mowery, Stephanie A; Drucker, Daniel J; D'Alessio, David A; Campbell, Jonathan E; Müller, Timo D; Perez-Tilve, Diego; Finan, Brian; Knerr, Patrick J

Translational and clinical development of therapeutic siRNA and ASOs: current industry practices, perspectives, and recommendations

治疗性siRNA和ASO的转化和临床开发:当前行业实践、观点和建议

Christensen, Jesper Kammersgaard; Colletti, Nicholas; Hooshfar, Shirin; Jiang, Rongrong Rosa; Kuo, Carol; Lindmark, Bosse; Lumen, Annie; Youssef, Amir S; Albertolle, Matthew; Aluri, Krishna C; Chen, Linzhi; Chen, Jingxian; Chopda, Girish; Chua, Xien Yu; Morais, Pedro; Dubois, Barent; Gibbons, Francis Frank; Gudey, Shyam Kumar; Gupta, Swati; Hood, Steve; Humphreys, Sara; Husser, Christophe; Huth, Felix; Jani, Darshana; Jian, Wenying; Kakuda, Thomas; Kurz, Jeffrey; Linnebjerg, Helle; Liu, Jing; Lohmann, Sabine; Niu, Tao; Root, Katharina; Singla, Sumeet; Tang, Chenxiao; Veluri, Ravikanth; Zhang, Guangnong Sunny; Zhang, Steven; Jawa, Vibha

A GLP-1 analogue optimized for cAMP-biased signaling improves weight loss in obese mice.

针对 cAMP 偏向信号传导优化的 GLP-1 类似物可改善肥胖小鼠的体重减轻

Douros Jonathan D, Novikoff Aaron, DuBois Barent, Rohlfs Rebecca, Mokrosinski Jacek, Hogendorf Wouter F J, Augustin Robert, Merkestein Myrte, Egaa Martini Lene Brandt, Linderoth Lars, Gerrard Elliot, Kodra Janos Tibor, Norlin Jenny, Roed Nikolaj Kulahin, Oldenburger Anouk, Mowery Stephanie A, Waldhoer Maria, Perez-Tilve Diego, Finan Brian, Reedtz-Runge Steffen, Müller Timo D, Knerr Patrick J

Theophylline Pharmacokinetics in Foetal Sheep: Maternal Metabolic Capacity is the Principal Driver

茶碱在胎羊体内的药代动力学:母体代谢能力是主要驱动因素

DuBois, Barent; Louey, Samantha; Giraud, George D; Cherala, Ganesh; Jonker, Sonnet S

Increased exposure of norethindrone in HIV+ women treated with ritonavir-boosted atazanavir therapy

接受利托那韦增强的阿扎那韦治疗的 HIV 感染女性体内炔诺酮暴露量增加

DuBois, Barent N; Atrio, Jessica; Stanczyk, Frank Z; Cherala, Ganesh

Perinatal growth restriction decreases diuretic action of furosemide in adult rats

围产期生长受限会降低呋塞米在成年大鼠中的利尿作用

DuBois, Barent N; Pearson, Jacob; Mahmood, Tahir; Nguyen, Duc; Thornburg, Kent; Cherala, Ganesh