日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Carbon capture in polymer-based electrolytes

聚合物基电解质中的碳捕获

Wang, Yang; Feric, Tony G; Tang, Jing; Fang, Chao; Hamilton, Sara T; Halat, David M; Wu, Bing; Celik, Hasan; Rim, Guanhe; DuBridge, Tara; Oshiro, Julianne; Wang, Rui; Park, Ah-Hyung Alissa; Reimer, Jeffrey A

Regression of EGFR positive established solid tumors in mice with the conditionally active T cell engager TAK-186

使用条件活性 T 细胞接合剂 TAK-186 可使小鼠中 EGFR 阳性的实体肿瘤消退

Danielle E Dettling, Eilene Kwok, Lucy Quach, Aakash Datt, Jeremiah D Degenhardt, Anand Panchal, Pui Seto, Jessica L Krakow, Russell Wall, Brian J Hillier, Ying Zhu, Maia Vinogradova, Robert B DuBridge, Chad May

Structural arrangement of the VH and VL domains in the COBRA™ T-cell engaging single-chain diabody

COBRA™ T细胞结合单链双抗体中VH和VL结构域的结构排列

Krakow, Jessica; Hammel, Michal; Zhu, Ying; Hillier, Brian J; Paolella, Bryce; Desmarais, Austin; Wall, Rusty; Chen, Tseng-Hui T; Pei, Rex; Karunatilake, Chulani; DuBridge, Robert; Vinogradova, Maia

CRISPR/Cas9 disruption of EpCAM Exon 2 results in cell-surface expression of a truncated protein targeted by an EpCAM specific T cell engager

利用 CRISPR/Cas9 技术破坏 EpCAM 外显子 2 会导致细胞表面表达截短蛋白,该截短蛋白可被 EpCAM 特异性 T 细胞衔接器靶向。

Andisheh Bagheri ,Patricia A Culp ,Robert B DuBridge ,Tseng-Hui Timothy Chen

COBRA™: a highly potent conditionally active T cell engager engineered for the treatment of solid tumors

COBRA™:一种高效条件活性 T 细胞接合剂,专为治疗实体肿瘤而设计

Anand Panchal, Pui Seto, Russell Wall, Brian J Hillier, Ying Zhu, Jessica Krakow, Aakash Datt, Elizabeth Pongo, Andisheh Bagheri, Tseng-Hui T Chen, Jeremiah D Degenhardt, Patricia A Culp, Danielle E Dettling, Maia V Vinogradova, Chad May, Robert B DuBridge

Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing

使用哺乳动物细胞展示和大规模并行焦磷酸测序对抗表皮生长因子受体抗体进行深度突变扫描

Charles M Forsyth, Veronica Juan, Yoshiko Akamatsu, Robert B DuBridge, Minhtam Doan, Alexander V Ivanov, Zhiyuan Ma, Dixie Polakoff, Jennifer Razo, Keith Wilson, David B Powers

The human G1m1 allotype associates with CD4+ T-cell responsiveness to a highly conserved IgG1 constant region peptide and confers an asparaginyl endopeptidase cleavage site

人类 G1m1 同种型与 CD4+ T 细胞对高度保守的 IgG1 恒定区肽的反应性相关,并赋予天冬酰胺内切肽酶裂解位点

M M Stickler, A Reddy, J M Xiong, P R Hinton, R DuBridge, F A Harding

The immunogenicity of humanized and fully human antibodies: residual immunogenicity resides in the CDR regions

人源化和全人抗体的免疫原性:残留免疫原性位于 CDR 区域

Fiona A Harding, Marcia M Stickler, Jennifer Razo, Robert B DuBridge

A function blocking anti-mouse integrin alpha5beta1 antibody inhibits angiogenesis and impedes tumor growth in vivo

阻断抗鼠整合素α5β1抗体的功能可抑制血管生成并阻碍体内肿瘤的生长

Vinay Bhaskar, Dong Zhang, Melvin Fox, Pui Seto, Melanie H L Wong, Pauline E Wales, David Powers, Debra T Chao, Robert B Dubridge, Vanitha Ramakrishnan

In vitro cloning of complex mixtures of DNA on microbeads: physical separation of differentially expressed cDNAs

微珠上复杂 DNA 混合物的体外克隆:差异表达 cDNA 的物理分离

S Brenner, S R Williams, E H Vermaas, T Storck, K Moon, C McCollum, J I Mao, S Luo, J J Kirchner, S Eletr, R B DuBridge, T Burcham, G Albrecht