日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Selective disruption of lipid peroxide homeostasis in intratumoral regulatory T cells by targeting FSP1 enhances cancer immunity

通过靶向FSP1选择性地破坏肿瘤内调节性T细胞中的脂质过氧化物稳态,可增强肿瘤免疫力。

Castillo, Jesse Garcia; Silveria, Stephanie; Schirokauer, Leo; Sauquet, Antoine; Hung, Jessica; Jaworski, Grace; Hendricks, Joseph M; Sul, Hei Sook; Olzmann, James A; DuPage, Michel

Domvanalimab and zimberelimab in advanced gastric, gastroesophageal junction or esophageal cancer: a phase 2 trial

Domvanalimab 和 zimberelimab 治疗晚期胃癌、胃食管交界处癌或食管癌:一项 II 期试验

Janjigian, Yelena Y; Oh, Do-Youn; Pelster, Meredith; Wainberg, Zev A; Prusty, Subhransu; Nelson, Sandahl; DuPage, Amy; Thompson, Amy; Koralek, Daniel O; Sison, Edward Allan R; Rha, Sun Young

Cellular mechanisms underlying beneficial versus detrimental effects of bacterial antitumor immunotherapy.

细菌抗肿瘤免疫疗法产生有益作用与有害作用的细胞机制。

Garcia Castillo Jesse, Fernandez Sebastian, Campbell Timothy, Gonzalez Ventura Diego, Williams Jacob, Ybarra Julia, Flores Hernandez Nicole, Wells Elina, Portnoy Daniel A, DuPage Michel

Age-related remodeling of the sialoglycans dampens murine CD8(+) T cell function

与年龄相关的唾液酸糖链重塑会抑制小鼠 CD8(+) T 细胞功能。

Zhang, Hanlin; Tsui, C Kimberly; Castillo, Jesse Garcia; Kim, Esther Jeong Yoon; Evangelista, Audrey; Liu, HengChen; Joe, Larry K; Twells, Nicholas; Robey, Ellen A; Mahal, Lara K; DuPage, Michel; Dillin, Andrew

Listeria monocytogenes adenosine auxotrophs are impaired for intracellular and extracellular growth but retain potent immunogenicity

单核细胞增生李斯特菌腺苷营养缺陷型菌株的细胞内和细胞外生长能力受损,但仍具有很强的免疫原性。

Ying Feng # ,Mariya Lobanovska # ,Jenna Vickery ,Jesse Garcia Castillo ,Leslie Güereca ,Shannon K Chang ,Michel DuPage ,Daniel A Portnoy

TLR2 signaling uniquely destabilizes tumor Tregs to promote cancer immunotherapy

TLR2信号通路能够独特地破坏肿瘤Treg细胞的稳定性,从而促进癌症免疫治疗。

Campbell, Timothy F; Castillo, Jesse Garcia; Fernandez, Sebastian; Ventura, Diego Gonzalez; Vickery, Jenna; Homentcovschi, Stefan; Hernandez, Nicole Flores; Ybarra, Julia; Portnoy, Daniel A; DuPage, Michel

Selective disruption of lipid peroxide homeostasis in intratumoral regulatory T cells by targeting FSP1 enhances cancer immunity

通过靶向FSP1选择性地破坏肿瘤内调节性T细胞中的脂质过氧化物稳态,可增强肿瘤免疫力。

Castillo, Jesse Garcia; Silveria, Stephanie; Sauquet, Antoine; Schirokauer, Leo; Hendricks, Joseph; Sul, Hei Sook; Olzmann, James A; DuPage, Michel

A mass cytometry method pairing T cell receptor and differentiation state analysis

一种结合T细胞受体和分化状态分析的质谱流式细胞术方法

Garcia Castillo, Jesse; DeBarge, Rachel; Mende, Abigail; Tenvooren, Iliana; Marquez, Diana M; Straub, Adrian; Busch, Dirk H; Spitzer, Matthew H; DuPage, Michel

Hyperactivating EZH2 to augment H3K27me3 levels in regulatory T cells enhances immune suppression by driving early effector differentiation

过度激活 EZH2 以增加调节性 T 细胞中 H3K27me3 的水平,可通过促进早期效应细胞分化来增强免疫抑制作用。

Janneke G C Peeters,Stephanie Silveria,Merve Ozdemir,Srinivas Ramachandran,Michel DuPage

Hyperactivating EZH2 to augment H3K27me3 levels in regulatory T cells enhances immune suppression by driving early effector differentiation

过度激活 EZH2 以增加调节性 T 细胞中 H3K27me3 的水平,可通过促进早期效应细胞分化来增强免疫抑制作用。

Janneke G C Peeters ,Stephanie Silveria ,Merve Ozdemir ,Srinivas Ramachandran ,Michel DuPage