Duan Wenzhen相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Vascular smooth muscle cell loss, but not neuroinflammation, drives cerebrovascular reactivity impairment in Alzheimer's disease.

阿尔茨海默病中脑血管反应性受损的驱动因素是血管平滑肌细胞丢失，而不是神经炎症。

期刊:Alzheimers & Dementia

影响因子:11.1

doi:10.1002/alz.71209

Yang Xiuli, Li Yuguo, Yao Minmin, Bibic Adnan, Duan Wenzhen, Lu Hanzhang, Wei Zhiliang

阿尔茨海默症

细胞生物学

发表日期：2026

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Neurovascular and metabolic dysfunction with cell type-specific transcriptomic changes in presymptomatic 5XFAD mice

5XFAD小鼠在症状出现前表现出神经血管和代谢功能障碍以及细胞类型特异性转录组变化。

期刊:Fluids and Barriers of the Cns

影响因子:6.2

doi:10.1186/s12987-025-00756-4

Yao, Minmin; Sun, Na; Linville, Raleigh; Wei, Zhiliang; Kakazu, Aaron; Ouyang, Yuxiao; Li, Ruoxuan; Du, Lida; Wang, Haitong; Zhou, Yuan; Jiang, Yanli; Zhang, Ziqin; Li, Anna; Garcia, Francisco J; Lu, Hanzhang; Xu, Jiadi; Kellis, Manolis; Heiman, Myriam; Duan, Wenzhen

细胞生物学

发表日期：2026

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Progressively reduced cerebral oxygen metabolism and elevated plasma NfL levels in the zQ175DN mouse model of Huntington's disease.

亨廷顿病 zQ175DN 小鼠模型中脑氧代谢逐渐降低，血浆 NfL 水平升高。

期刊:Experimental Neurology

影响因子:4.2

doi:10.1016/j.expneurol.2025.115461

Wu Qian, Yao Minmin, Liu Hongshuai, Kakazu Aaron, Ouyang Yuxiao, Liu Chang, Li Ruoxuan, Yang Fan, Wang Anqi, Surasinghe Sharmane, Gerochi Damien, Baldo Barbara, Jahn Stefanie, Tang Haiying, Lu Hanzhang, Wei Zhiliang, Duan Wenzhen

发表日期：2025

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The glymphatic system in Huntington's disease

亨廷顿病中的淋巴系统

期刊:Journal of Huntingtons Disease

影响因子:3.1

doi:10.1177/18796397251331436

Duan, Wenzhen; Zhou, Yuan; Liu, Hongshuai

发表日期：2025

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Vascular smooth muscle cell loss, but not neuroinflammation, drives cerebrovascular reactivity impairment in Alzheimer's disease

阿尔茨海默病中脑血管反应性受损是由血管平滑肌细胞丢失而非神经炎症引起的。

doi:10.64898/2025.12.01.691642

Yang, Xiuli; Li, Yuguo; Yao, Minmin; Bibic, Adnan; Duan, Wenzhen; Lu, Hanzhang; Wei, Zhiliang

阿尔茨海默症

细胞生物学

发表日期：2025

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Distinguishing microgliosis and tau deposition in the mouse brain using paramagnetic and diamagnetic susceptibility source separation

利用顺磁和抗磁磁化率源分离区分小鼠脑内的微胶质细胞增生和tau蛋白沉积

doi:10.1162/imag_a_00467

Joshi, Jayvik; Yao, Minmin; Kakazu, Aaron; Ouyang, Yuxiao; Duan, Wenzhen; Aggarwal, Manisha

细胞生物学

发表日期：2025

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Vascular Microbleeds Without Brain Atrophy: A Microvascular Signature of Mid-Stage 5xFAD Pathology

无脑萎缩的血管微出血：5xFAD 中期病理的微血管特征

doi:10.64898/2025.12.08.692809

Yang, Xiuli; Li, Yuguo; Bibic, Adnan; Wang, Jiekang; Wan, Mei; Duan, Wenzhen; Lu, Hanzhang; Wei, Zhiliang

发表日期：2025

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Cell type-specific contributions to impaired blood-brain barrier and cerebral metabolism in presymptomatic 5XFAD mice.

细胞类型特异性因素对无症状 5XFAD 小鼠血脑屏障受损和脑代谢的影响

doi:10.1101/2025.04.23.650260

Yao Minmin, Sun Na, Linville Raleigh, Wei Zhiliang, Kakazu Aaron, Ouyang Yuxiao, Li Ruoxuan, Du Lida, Wang Haitong, Zhou Yuan, Jiang Yanli, Zhang Ziqin, Li Anna, Lu Hanzhang, Xu Jiadi, Kellis Manolis, Heiman Myriam, Duan Wenzhen

细胞生物学

发表日期：2025

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Roscovitine, a CDK Inhibitor, Reduced Neuronal Toxicity of mHTT by Targeting HTT Phosphorylation at S1181 and S1201 In Vitro.

CDK抑制剂Roscovitine通过靶向S1181和S1201位点的HTT磷酸化，降低了mHTT的神经元毒性

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms252212315

Liu Hongshuai, McCollum Ainsley, Krishnaprakash Asvini, Ouyang Yuxiao, Shi Tianze, Ratovitski Tamara, Jiang Mali, Duan Wenzhen, Ross Christopher A, Jin Jing

发表日期：2024

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The potential of gene editing for Huntington's disease

基因编辑在亨廷顿病治疗中的潜力

期刊:Trends in Neurosciences

影响因子:15.1

doi:10.1016/j.tins.2023.02.005

Duan, Wenzhen; Urani, Ece; Mattson, Mark P

发表日期：2023

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