Dubensky Thomas W Jr相关文献与解析，生知库

Hanson, William G; Benanti, Erin L; Lemmens, Edward E; Liu, Weiqun; Skoble, Justin; Leong, Meredith L; Rae, Chris S; Fassò, Marcella; Brockstedt, Dirk G; Chen, Chen; Portnoy, Daniel A; Dubensky, Thomas W Jr; Lauer, Peter

发表日期：2019

文献求助收藏

Recombinant Listeria promotes tumor rejection by CD8(+) T cell-dependent remodeling of the tumor microenvironment

重组李斯特菌通过CD8(+) T细胞依赖性地重塑肿瘤微环境来促进肿瘤排斥

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1801910115

Deng, Weiwen; Lira, Victor; Hudson, Thomas E; Lemmens, Edward E; Hanson, William G; Flores, Ruben; Barajas, Gonzalo; Katibah, George E; Desbien, Anthony L; Lauer, Peter; Leong, Meredith L; Portnoy, Daniel A; Dubensky, Thomas W Jr

New Cancer Immunotherapy Agents in Development: a report from an associated program of the 31(st)Annual Meeting of the Society for Immunotherapy of Cancer, 2016

正在研发的新型癌症免疫治疗药物：2016年癌症免疫治疗学会第31届年会相关项目报告

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.6

doi:10.1186/s40425-017-0253-2

Adusumilli, Prasad S; Cha, Edward; Cornfeld, Mark; Davis, Thomas; Diab, Adi; Dubensky, Thomas W Jr; Evans, Elizabeth; Grogan, Jane L; Irving, Bryan A; Leidner, Rom S; Olwill, Shane A; Soon-Shiong, Patrick; Triebel, Frederic; Tuck, David; Bot, Adrian; Dansey, Roger D; Drake, Charles G; Freeman, Gordon J; Ibrahim, Ramy; Patel, Salil; Chen, Daniel S

A STING Agonist Given with OX40 Receptor and PD-L1 Modulators Primes Immunity and Reduces Tumor Growth in Tolerized Mice

STING激动剂与OX40受体和PD-L1调节剂联合使用可增强免疫力并减少耐受小鼠的肿瘤生长。

期刊:Cancer Immunology Research

影响因子:8.2

doi:10.1158/2326-6066.CIR-16-0284

Foote, Jeremy B; Kok, Marleen; Leatherman, James M; Armstrong, Todd D; Marcinkowski, Bridget C; Ojalvo, Laureen S; Kanne, David B; Jaffee, Elizabeth M; Dubensky, Thomas W Jr; Emens, Leisha A

Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors.

放射疗法联合新型 STING 靶向寡核苷酸可使已形成的肿瘤消退

期刊:Cancer Research

影响因子:16.6

doi:10.1158/0008-5472.CAN-14-3619

Baird Jason R, Friedman David, Cottam Benjamin, Dubensky Thomas W Jr, Kanne David B, Bambina Shelly, Bahjat Keith, Crittenden Marka R, Gough Michael J

Virological and preclinical characterization of a dendritic cell targeting, integration-deficient lentiviral vector for cancer immunotherapy

对靶向树突状细胞的整合缺陷型慢病毒载体进行病毒学和临床前表征，用于癌症免疫治疗

期刊:Journal of Immunotherapy

影响因子:2.9

doi:10.1097/CJI.0000000000000067

Odegard, Jared M; Kelley-Clarke, Brenna; Tareen, Semih U; Campbell, David J; Flynn, Patrick A; Nicolai, Christopher J; Slough, Megan M; Vin, Chintan D; McGowan, Patrick J; Nelson, Lisa T; Ter Meulen, Jan; Dubensky, Thomas W Jr; Robbins, Scott H

Attenuated Listeria monocytogenes vectors overcome suppressive plasma factors during HIV infection to stimulate myeloid dendritic cells to promote adaptive immunity and reactivation of latent virus.

减毒的单核细胞增生李斯特菌载体克服 HIV 感染期间的血浆抑制因子，刺激髓系树突状细胞，促进适应性免疫和潜伏病毒的重新激活

期刊:Aids Research and Human Retroviruses

影响因子:1.1

doi:10.1089/AID.2014.0138

Miller Elizabeth A, Spadaccia Meredith R, Norton Thomas, Demmler Morgan, Gopal Ramya, O'Brien Meagan, Landau Nathaniel, Dubensky Thomas W Jr, Lauer Peter, Brockstedt Dirk G, Bhardwaj Nina

A live-attenuated Listeria vaccine (ANZ-100) and a live-attenuated Listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase I studies of safety and immune induction

用于晚期癌症的减毒活李斯特菌疫苗（ANZ-100）和表达间皮素的减毒活李斯特菌疫苗（CRS-207）：I期安全性和免疫诱导研究

期刊:Clinical Cancer Research

影响因子:10.2

doi:10.1158/1078-0432.CCR-11-2121

Le, Dung T; Brockstedt, Dirk G; Nir-Paz, Ran; Hampl, Johannes; Mathur, Shruti; Nemunaitis, John; Sterman, Daniel H; Hassan, Raffit; Lutz, Eric; Moyer, Bentley; Giedlin, Martin; Louis, Jana-Lynn; Sugar, Elizabeth A; Pons, Alice; Cox, Andrea L; Levine, Jordana; Murphy, Aimee Luck; Illei, Peter; Dubensky, Thomas W Jr; Eiden, Joseph E; Jaffee, Elizabeth M; Laheru, Daniel A

Impact of preexisting vector-specific immunity on vaccine potency: characterization of listeria monocytogenes-specific humoral and cellular immunity in humans and modeling studies using recombinant vaccines in mice

预先存在的载体特异性免疫对疫苗效力的影响：人类单核细胞增生李斯特菌特异性体液和细胞免疫的特征分析以及利用小鼠重组疫苗进行的模型研究

期刊:Infection and Immunity

影响因子:2.8

doi:10.1128/IAI.01274-08

Leong, Meredith L; Hampl, Johannes; Liu, Weiqun; Mathur, Shruti; Bahjat, Keith S; Luckett, William; Dubensky, Thomas W Jr; Brockstedt, Dirk G

Constitutive Activation of the PrfA regulon enhances the potency of vaccines based on live-attenuated and killed but metabolically active Listeria monocytogenes strains

PrfA调节子的组成型激活增强了基于减毒活菌株和灭活但代谢活跃的单核细胞增生李斯特菌菌株的疫苗效力。

期刊:Infection and Immunity

影响因子:2.8

doi:10.1128/IAI.00390-08

Lauer, Peter; Hanson, Bill; Lemmens, Edward E; Liu, Weiqun; Luckett, William S; Leong, Meredith L; Allen, Heather E; Skoble, Justin; Bahjat, Keith S; Freitag, Nancy E; Brockstedt, Dirk G; Dubensky, Thomas W Jr

A Potent and Effective Suicidal Listeria Vaccine Platform

一种强效且有效的自杀性李斯特菌疫苗平台

Recombinant Listeria promotes tumor rejection by CD8(+) T cell-dependent remodeling of the tumor microenvironment

重组李斯特菌通过CD8(+) T细胞依赖性地重塑肿瘤微环境来促进肿瘤排斥

New Cancer Immunotherapy Agents in Development: a report from an associated program of the 31(st)Annual Meeting of the Society for Immunotherapy of Cancer, 2016

正在研发的新型癌症免疫治疗药物：2016年癌症免疫治疗学会第31届年会相关项目报告

A STING Agonist Given with OX40 Receptor and PD-L1 Modulators Primes Immunity and Reduces Tumor Growth in Tolerized Mice

STING激动剂与OX40受体和PD-L1调节剂联合使用可增强免疫力并减少耐受小鼠的肿瘤生长。

Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors.

放射疗法联合新型 STING 靶向寡核苷酸可使已形成的肿瘤消退

Virological and preclinical characterization of a dendritic cell targeting, integration-deficient lentiviral vector for cancer immunotherapy

对靶向树突状细胞的整合缺陷型慢病毒载体进行病毒学和临床前表征，用于癌症免疫治疗

Attenuated Listeria monocytogenes vectors overcome suppressive plasma factors during HIV infection to stimulate myeloid dendritic cells to promote adaptive immunity and reactivation of latent virus.

减毒的单核细胞增生李斯特菌载体克服 HIV 感染期间的血浆抑制因子，刺激髓系树突状细胞，促进适应性免疫和潜伏病毒的重新激活

A live-attenuated Listeria vaccine (ANZ-100) and a live-attenuated Listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase I studies of safety and immune induction

用于晚期癌症的减毒活李斯特菌疫苗（ANZ-100）和表达间皮素的减毒活李斯特菌疫苗（CRS-207）：I期安全性和免疫诱导研究

Impact of preexisting vector-specific immunity on vaccine potency: characterization of listeria monocytogenes-specific humoral and cellular immunity in humans and modeling studies using recombinant vaccines in mice

预先存在的载体特异性免疫对疫苗效力的影响：人类单核细胞增生李斯特菌特异性体液和细胞免疫的特征分析以及利用小鼠重组疫苗进行的模型研究

Constitutive Activation of the PrfA regulon enhances the potency of vaccines based on live-attenuated and killed but metabolically active Listeria monocytogenes strains

PrfA调节子的组成型激活增强了基于减毒活菌株和灭活但代谢活跃的单核细胞增生李斯特菌菌株的疫苗效力。